| Type | Description |
|---|---|
| Definition | mitogen activated protein kinase kinase 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-07-21 11:54:00 | Matrine-type alkaloids exert endothelial protective effects against advanced glycation end products induced reactive oxygen species-mediated apoptosis by targeting MKK3/6/p38MAPK signaling and enhancing their phosphorylation. | 29197828 |
| 2017-10-21 12:51:00 | Data suggest that Mapk14/p38alpha is activated and forms cystine disulfide-bound heterodimer with Map2k3/Mkk3 in cardiomyocytes and isolated hearts during oxidative stress (exposure to hydrogen peroxide). (Mapk14, mitogen-activated protein kinase 14; Mkk3 = mitogen-activated protein kinase kinase 3) | 28739872 |
| 2012-08-04 11:43:00 | Superoxide anion is an important signaling molecule for activating the MKK3/6-p38 cascade, which is requisite for inducing tumor necrosis factor (TNF)alpha in microglia. | 21981804 |
| 2010-01-21 00:00:00 | Rap1, MKK3/6, and p38 MAPK have a role in the induction of mGluR-dependent LTD by directly coupling to receptor trafficking machineries to facilitate the loss of synaptic AMPA receptors [map2k3, also called MKK3] | 14709549 |
| Type | IDs |
|---|---|
| Synonymous | Mek3, Mkk3 |
| Gene |
UniProtKB-ID:
B1H230_RAT,
Q498S1_RAT
UniprotKB:
B1H230,
Q498S1
UniParc:
UPI00005904B4,
UPI0000500D3E
EMBL:
CH473948,
AABR07029719,
BC100095,
BC160839,
AABR07029710
Ensembl:
ENSRNOG00000049132,
ENSRNOG00000006612
KO:
rno:303200
|
| Nucleutide sequences |
EMBL-CDS:
EDM04673.1,
AAI60839.1,
AAI00096.1
Gene_ORFName:
rCG_34789
Ensembl_TRS:
ENSRNOT00000073792,
ENSRNOT00000008679
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000065373,
ENSRNOP00000008679
RefSeq:
NP_001094144.1
|
| Others |
UniRef100:
UniRef100_Q498S1,
UniRef100_B1H230
UniRef90:
UniRef90_B1H230
UniRef50:
UniRef50_O09110
UniGene:
Rn.100064
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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