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3021 H3F3B

3021

H3F3B

H3 histone family member 3B

protein-coding

Homo sapiens

基因描述

Type Description
Definition H3 histone family member 3B

研究结论

Date Results Publications
2021-03-28 19:07:00 Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression. 33067396
2018-11-03 10:52:00 SNPs in SLC22A3 and H3F3B may influence lipid levels through altering the expression of local genes. SNPs in H3F3B may influence CAD risk through altering the expression of local genes. 29894858
2018-08-25 11:34:00 evidence that a SNP in the gene H3F3B is associated with a broad schizophrenia spectrum phenotype and also alters the function of a miRNA target site within the of the gene. 29529098
2018-06-09 11:19:00 It has been suggested that H3.3K36M mutant proteins alter epigenomes of specific progenitor cells, which in turn lead to cellular transformation and tumorigenesis. 28129023
2017-12-09 11:23:00 Report H3F3A/B mutations in cell tumors of bone, chondroblastomas, and aneurysmal bone cysts. 28882701

名称对应

Type IDs
Synonymous H3.3B
Gene
UniProtKB-ID: H33_HUMAN, B2R4P9_HUMAN
UniprotKB: P84243, B2R4P9
UniParc: UPI00000007B0
EMBL: X05857, M11354, BC067757, BC017558, BC012813, BC081561, BC006497, AL512343, BC108701, CH471098, M11353, BC029405, X05856, BC066901, Z48950, BC001124, AK311905, BX537379, X05855, CH471099, BC081560, AF218029, BC095447, BC038989
Ensembl: ENSG00000163041, ENSG00000132475
KO: hsa:3020, hsa:3021
Nucleutide sequences
EMBL-CDS: CAA88778.1, AAA52654.1, AAH81561.1, AAH81560.1, CAD97621.1, AAI08702.1, AAH38989.1, AAH01124.1, AAH17558.1, AAG17271.1, AAA52653.1, CAA29288.1, AAH06497.1, AAH29405.1, AAH95447.1, AAH12813.1, BAG34846.1, EAW89318.1, EAW69773.1, EAW69771.1, EAW69770.1, EAW69772.1, EAW89319.1, EAW89317.1
Gene_ORFName: PP781, hCG_1984517, hCG_1989319
Ensembl_TRS: ENST00000666609, ENST00000586607, ENST00000366815, ENST00000366816, ENST00000589599, ENST00000366813, ENST00000254810, ENST00000655399, ENST00000661429, ENST00000587560
Protein sequencees
Ensembl_PRO: ENSP00000466020, ENSP00000355778, ENSP00000468714, ENSP00000499385, ENSP00000465813, ENSP00000499800, ENSP00000499275, ENSP00000355780, ENSP00000254810, ENSP00000355781
RefSeq: NP_005315.1
Others
UniRef100: UniRef100_P84243
UniRef90: UniRef90_P84243
UniRef50: UniRef50_P84243
UniGene: Hs.180877
CCDS: CCDS1550.1, CCDS11729.1

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研究热度

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