| Type | Description |
|---|---|
| Definition | telomerase reverse transcriptase |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 10:14:00 | Reactive oxygen species up-regulation inhibits TERT expression, suppresses TERT activity and facilitates premature ovarian failure. | 30338789 |
| 2018-09-08 10:28:00 | Curcumin may be a good candidate to improve lifespan of rADSCs through promoting TERT gene expression. | 29017189 |
| 2018-09-01 11:10:00 | TERT was expressed in the basilar membranes during the first postnatal week. In vitro, TERT expression in progenitor cells reached a maximum at day 4 after culture and decreased as the culture time prolonged or the cell passage number increased. These results led us to hypothesize that TERT may be involved in the development of the cochlea and in maintaining the proliferation ability of progenitor cells. | 29436610 |
| 2017-03-04 11:59:00 | Proliferation rate, telomerase activity, telomere length, and differentiation to cholinergic neuron-like cells (CNLCs) were observed to increase. Though, the expression level of telomerase reverse transcriptase gene increased, but CTC1 and TEN1 genes from Ctc1-Stn1-Ten1 complex encoding proteins with regulatory function significantly decreased | 27251157 |
| 2016-07-16 10:41:00 | Histone deacetylase inhibition induces TERT transcription and promoter activation. At the protein level in contrast, HDAC inhibition decreases TERT protein abundance through enhanced degradation, which decreases telomerase activity and induces senescence. | 26505494 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TERT_RAT
UniprotKB:
Q673L6
UniParc:
UPI000042811E,
UPI000042811D,
UPI00001CE6A2
EMBL:
AC123569,
DQ021473,
AY539717,
AJ440965,
AY539720,
BK000660,
AY539718,
AY539719,
AJ440966
Ensembl:
ENSRNOG00000025327
KO:
rno:301965
|
| Nucleutide sequences |
EMBL-CDS:
AAT09125.1,
CAD29524.1,
AAT09126.1,
DAA01427.1,
AAT09127.1,
AAY40300.1,
AAT09124.1,
CAD29525.2
Ensembl_TRS:
ENSRNOT00000022683
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000022683
RefSeq:
NP_445875.1,
XP_017444567.1,
XP_008756906.1,
XP_008756905.1
|
| Others |
UniRef100:
UniRef100_Q673L6
UniRef90:
UniRef90_Q673L6
UniRef50:
UniRef50_O14746
UniGene:
Rn.48802
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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