| Type | Description |
|---|---|
| Definition | histone cluster 1 H2B family member d |
| Date | Results | Publications |
|---|---|---|
| 2019-10-26 12:20:00 | We report cryo-EM structures of human Dot1L bound to (1) H2BK120Ub and (2) unmodified nucleosome substrates at 3.5 A and 4.9 A, respectively. Comparison of both structures, complemented with biochemical experiments, provides critical insights into the mechanism of Dot1L stimulation by H2BK120Ub. | 30981630 |
| Type | IDs |
|---|---|
| Synonymous | H2B.1B, H2B/a, H2B/b, H2B/g, H2B/h, H2B/k, H2B/l, H2BFA, H2BFB, H2BFG, H2BFH, H2BFK, H2BFL, HIRIP2, HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI, dJ221C16.6 |
| Gene |
UniProtKB-ID:
H2B1C_HUMAN,
H2B1D_HUMAN,
A0A024QZZ7_HUMAN
UniprotKB:
P62807,
P58876,
A0A024QZZ7
UniParc:
UPI0000000C24,
UPI0000001BD3
EMBL:
AF531288,
M60751,
AL353759,
M60750,
BC106899,
AF531287,
Z80783,
BC101748,
AL031777,
BC101655,
Z80780,
BC101653,
BC001131,
AJ223353,
Z80779,
CH471087,
AF531292,
BC096122,
BC009612,
AF531290,
Z80782,
BC096120,
BC101750,
BC096123,
AF531286,
AF531289,
BC002842
Ensembl:
ENSG00000273802,
ENSG00000158373,
ENSG00000278588,
ENSG00000274290,
ENSG00000277224,
ENSG00000180596
KO:
hsa:8347,
hsa:8343,
hsa:8344,
hsa:3017,
hsa:8339,
hsa:8346
|
| Nucleutide sequences |
EMBL-CDS:
AAI01751.1,
AAI06900.1,
AAI01749.1,
AAN06688.1,
AAN06692.1,
CAB02541.1,
CAB02545.1,
AAH96122.1,
CAB02542.1,
AAN06686.1,
AAI01654.1,
AAH96123.1,
AAA63189.1,
AAN06689.1,
AAH96120.1,
AAN06690.1,
CAB02544.1,
AAI01656.1,
AAH02842.1,
CAA11277.1,
AAA63190.1,
AAN06687.1,
EAW55536.1,
EAW55535.1
Gene_ORFName:
hCG_1640483
Ensembl_TRS:
ENST00000634910,
ENST00000396984,
ENST00000314332,
ENST00000377733,
ENST00000356530,
ENST00000614097,
ENST00000541790,
ENST00000377777,
ENST00000289316
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000445633,
ENSP00000366962,
ENSP00000380180,
ENSP00000348924,
ENSP00000321744,
ENSP00000483237,
ENSP00000489317,
ENSP00000289316,
ENSP00000367008
RefSeq:
NP_619790.1,
XP_005249096.1,
NP_066407.1
|
| Others |
UniRef100:
UniRef100_P58876,
UniRef100_P62807
UniRef90:
UniRef90_P58876,
UniRef90_P62807
UniRef50:
UniRef50_P62807,
UniRef50_P58876
UniGene:
Hs.591797
CCDS:
CCDS4603.1,
CCDS4584.1,
CCDS4594.1,
CCDS4588.1,
CCDS4592.1,
CCDS4587.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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