Ugt1a8 - UDP glucuronosyltransferase family 1 member A8-BMKCloudï½ç¾è¿å®¢äº

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301595 Ugt1a8

基因描述

Type	Description
Definition	UDP glucuronosyltransferase family 1 member A8

研究结论

Date	Results	Publications
2010-01-21 00:00:00	Studies of their activities and tissue expression suggest complementary functions of UGT1A8 and UGT1A7 isoforms in xenobiotic metabolism.	15502008

名称对应

Type	IDs
Synonymous	UDPGT 1-8, Ugt1, Ugt1a9
Gene	UniProtKB-ID: Q6T5E7_RAT UniprotKB: Q6T5E7 UniParc: UPI00001CAB97 EMBL: AC120922, AY435135, CH473997, AABR07068281 Ensembl: ENSRNOG00000018740 KO: rno:301595
Nucleutide sequences	EMBL-CDS: EDL92107.1, AAR95636.1 Gene_ORFName: rCG_55639 Ensembl_TRS: ENSRNOT00000066839
Protein sequencees	Ensembl_PRO: ENSRNOP00000063634 RefSeq: NP_787040.2
Others	UniRef100: UniRef100_Q6T5E7 UniRef90: UniRef90_Q64634 UniRef50: UniRef50_Q9HAW9 UniGene: Rn.26489

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
20610558	Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro. Drug Metab. Dispos. Judith Bellemare , MÃ©lanie Rouleau , Hugo Girard , Mario Harvey , Chantal Guillemette	2010-10-01	UGT1A10, UGT1A8, UGT1A7, UGT1A6, UGT1A9, UGT1A4, UGT1A1, UGT1A3
20308471	Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans. Drug Metab. Dispos. Sophie E Rowbotham , Nicola A Illingworth , Ann K Daly , Gareth J Veal , Alan V Boddy	2010-07-01	UGT1A10, UGT1A8, UGT1A7, UGT1A6, UGT1A9, UGT1A4, UGT1A1, UGT1A3, UGT2B4, UGT2B7, UGT2B15, UGT2B17
20056724	Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples. Drug Metab. Dispos. Walter Brand , Marelle G Boersma , Hanneke Bik , Elisabeth F Hoek-van den Hil , Jacques Vervoort , Denis Barron , Walter Meinl , Hansruedi Glatt , Gary Williamson , Peter J van Bladeren , Ivonne M C M Rietjens	2010-04-01	SULT1C4, SULT1B1, UGT1A10, UGT1A8, UGT1A7, UGT1A9, UGT1A1, UGT1A3, SULT1E1, SULT1A2, SULT1A1, SULT1A3, SULT1C2, SULT2A1, UGT2B4, UGT2B7, UGT2B15
19996319	Modulation of the human glucuronosyltransferase UGT1A pathway by splice isoform polypeptides is mediated through protein-protein interactions. J Biol Chem Judith Bellemare , MÃ©lanie Rouleau , Mario Harvey , Chantal Guillemette	2010-02-05	-
17179145	Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation. J Biol Chem Theresa N OperaÃ±a , Robert H Tukey	2007-02-16	-
16141793	Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily. Pharmacogenet. Genomics Peter I Mackenzie , Karl Walter Bock , Brian Burchell , Chantal Guillemette , Shin-ichi Ikushiro , Takashi Iyanagi , John O Miners , Ida S Owens , Daniel W Nebert	2005-10-01	Ugt1a6, Ugt1a7c, Ugt1a1, Ugt1a8, Ugt1a9-ps, Ugt1a2, Ugt1a3, Ugt1a9, Ugt1a5, Ugt1a4-ps, UGT2A1, UGT1A12P, UGT1A11P, UGT1A2P, UGT2A2
14672974	Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation. Genome Res. Theresa Zhang , Peter Haws , Qiang Wu	2004-01-01	Pcdha10, Gcnt2, Plec, Pcdha12, Ugt1a2, Ugt1a10, Ugt1a@, Ugt1a7c, Ugt1a5, Ugt1a9, Ugt1a6b, Ugt1a1, Ugt1a6a, Pcdhga6, Ugt1a6, Pcdha4, Pcdha13, Pcdha10, Pcdha12, Pcdha3, Pcdha8, Pcdhgc3, Ugt1a7c, Nr3c1, Nos1, Ugt1a1, Pcdhb12, Pcdhb2l, Pcdhga4, Pcdhga9, Pcdhga11, Gcnt3, Pcdhga7, Pcdhga5, Pcdhb16, Pcdhb15, Pcdhb14, Pcdhb11, Pcdhb10, Pcdhb7, Pcdhb6, Pcdhb5, Pcdhb4, Pcdhb3, Ugt1a8, Gcnt2, Pcdhb22, Pcdhb21, Ugt1a9-ps, Pcdhb1, Pcdhga8, Pcdhgb7, Pcdhgb8, Pcdha1, Pcdha2, Pcdha5, Pcdha6, Pcdha7, Pcdha9, Pcdhac1, Pcdhac2, Pcdha11, Ugt1a2, Ugt1a3, Ugt1a9, Ugt1a@, Pcdhga2, Pcdhga3, Pcdhga10, Pcdhga12, Pcdhb17, Pcdhb18, Pcdhb19, Pcdhga1, Ugt1a5, Pcdhgc5, Pcdhgc4, Plec, Ugt1a4-ps, Pcdhb8, Pcdhb20, pcdhb, pcdh1g22, pcdh2g12, pcdh2ac, pcdh2ab2, pcdh2ab1, pcdh2ab3, pcdh2ab5, pcdh2ab6, pcdh2ab7, pcdh2ab8, pcdh2ab9, pcdh2aa1, pcdh2aa3, pcdh2ab10, pcdh2ab11, pcdh2ab12, pcdh2aa15
11854153	Glucuronidation of acetaminophen catalyzed by multiple rat phenol UDP-glucuronosyltransferases. Drug Metab. Dispos. Fay K Kessler , Marissa R Kessler , Diana J Auyeung , Joseph K Ritter	2002-03-01	-
11992647	Induction of UDP-glucuronosyltransferase 1A8 mRNA by 3-methylcholanthene in rat hepatoma cells. Biochem. Pharmacol. Yuet Kin Leung , John W Ho	2002-02-15	-

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