| Type | Description |
|---|---|
| Definition | ISL LIM homeobox 2a |
| Date | Results | Publications |
|---|---|---|
| 2019-04-20 11:01:00 | differentiation of the CaP motor neuron's stereotypic large inward and outward currents does not have a specific requirement for Islet2a. | 29927984 |
| 2017-08-12 10:07:00 | Isl2a is expressed in the lateral posterior mesoderm prior to angioblast migration. Isl2a-deficient angioblasts show disorganized migration to the midline to form axial vessels. Its expression is negatively regulated by Notch activity. It positively regulates flt4, a VEGF-C receptor repressed by Notch during angiogenesis. Isl2a may be an intermediate between Notch signaling and genetic programs controlling angioblasts. | 27126199 |
| 2013-02-02 11:57:00 | Prdm14 regulates caudal rimary axon outgrowth through activation of islet2 expression. | 23136389 |
| 2010-01-21 00:00:00 | primary motoneuron subtypes are likely to be specified by factors that act in parallel to or upstream of islet1 and islet2 | 16672347 |
| 2010-01-21 00:00:00 | Results show that PlexinA4, a transmembrane protein known to be a co-receptor for class III semaphorins, acts downstream of Islet2 to promote branching of the peripheral axons of the primary sensory neurons. | 15229183 |
| Type | IDs |
|---|---|
| Synonymous | ISL-2, isl2, wu:fc29g02, zfIsl-2 |
| Gene |
UniProtKB-ID:
ISL2A_DANRE,
B3DH43_DANRE
UniprotKB:
P53406,
B3DH43
UniParc:
UPI000012D8FA
EMBL:
BC162833,
U09403,
BC162631,
X88805,
D38453
Ensembl:
ENSDARG00000003971
KO:
dre:30157
|
| Nucleutide sequences |
EMBL-CDS:
CAA61283.1,
BAA07484.1,
AAA80274.1,
AAI62833.1,
AAI62631.1
Ensembl_TRS:
ENSDART00000012862
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000020636
RefSeq:
NP_571045.1,
XP_005163214.1,
XP_021326118.1,
XP_021326119.1
|
| Others |
UniRef100:
UniRef100_P53406
UniRef90:
UniRef90_P53406
UniRef50:
UniRef50_P53406
UniGene:
Dr.281
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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