| Type | Description |
|---|---|
| Definition | GLI family zinc finger 2a |
| Date | Results | Publications |
|---|---|---|
| 2016-01-30 10:50:00 | during vertebrate history GLI2 acquired a high level of complexity in the genetic mechanisms regulating its expression during spatiotemporal patterning of the central nervous system (CNS) and limbs. | 25715918 |
| 2014-08-23 10:13:00 | We show that Kif7 interacts with both Gli1 and Gli2a and suggest that it functions to sequester Gli proteins in the cytoplasm, in a manner analogous to the regulation of Ci by Cos2 in Drosophila. | 24339784 |
| 2010-09-27 11:56:00 | The Gli2 transcription factor localizes to the primary cilia of cells in the zebrafish embryo and that this localization is modulated by the activity of the Hedgehog pathway. | 20487519 |
| 2010-01-21 00:00:00 | The Gli2s play an early Hh-independent repressor role in the maintenance of neural progenitors and an Hh-dependent activating role during cell differentiation in the floor plate, branchial motor neurons, and sensory neurons. | 18060804 |
| 2010-01-21 00:00:00 | These results reveal divergent requirements for Gli1 and Gli2 in mouse and zebrafish and indicate that zebrafish Gli1 is an activator of Hh-regulated genes, while zebrafish Gli2 has minor roles as a repressor or activator of Hh targets. | 12620981 |
| Type | IDs |
|---|---|
| Synonymous | fc85b05, gli2, wu:fc85b05, yot, you-too |
| Gene |
UniProtKB-ID:
Q9YGS4_DANRE
UniprotKB:
Q9YGS4
UniParc:
UPI00000FCCDF
EMBL:
AF085746
KO:
dre:30154
|
| Nucleutide sequences |
EMBL-CDS:
AAD18135.2
|
| Protein sequencees |
RefSeq:
NP_571042.1
|
| Others |
UniRef100:
UniRef100_Q9YGS4
UniRef90:
UniRef90_Q9YGS4
UniRef50:
UniRef50_Q0VGT2
UniGene:
Dr.8091
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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