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30145 lft1

30145

lft1

lefty1

protein-coding

Danio rerio

基因描述

Type Description
Definition lefty1

研究结论

Date Results Publications
2018-07-07 12:02:00 Theauthors find that zebrafish lefty mutants exhibit excess Nodal signaling and increased specification of mesendoderm, resulting in embryonic lethality. 29215332
2016-02-13 10:58:00 Our data do not support the reaction-diffusion model, but instead, we propose that Nodal activates signaling in a temporal window that is defined by a miR-430-mediated delay of Lft1/2 translation 26506307
2012-05-26 11:30:00 results indicate that differential diffusivity is the major determinant of the differences in Nodal/Lefty range and provide biophysical support for reaction-diffusion models of activator/inhibitor-mediated patterning 22499809
2012-02-11 10:29:00 both Nodal and Bmp independently are required for lefty1 expression to assure unilateral Nodal activation and correct LR patterning 21980297
2011-12-03 10:26:00 Bmp represses Nodal signaling independently of lefty1 expression and through the activity of a ligand other than Bmp4. 21937597

名称对应

Type IDs
Synonymous antivin, atv, cb73, ik:tdsubc_2b12, xx:tdsubc_2b12
Gene
UniProtKB-ID: Q9PW55_DANRE
UniprotKB: Q9PW55
UniParc: UPI00000FD8F1
EMBL: AF172089
KO: dre:30145
Nucleutide sequences
EMBL-CDS: AAD47114.1
Protein sequencees
RefSeq: NP_571035.1
Others
UniRef100: UniRef100_Q9PW55
UniRef90: UniRef90_Q9W6I6
UniRef50: UniRef50_Q9W6I6
UniGene: Dr.81291

全选

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研究热度

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