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30122 wnt8a

30122

wnt8a

wingless-type MMTV integration site family, member 8a

protein-coding

Danio rerio

基因描述

Type Description
Definition wingless-type MMTV integration site family, member 8a

研究结论

Date Results Publications
2018-12-22 10:57:00 In the Wnt-receiving cells, Wnt8a on cytonemes triggers Wnt/beta-catenin-dependent gene transcription and proliferation. We show that cytoneme-based Wnt transport operates in diverse processes, including zebrafish development, murine intestinal crypt and human cancer organoids, demonstrating that Wnt transport by cytonemes and its control via the Ror2 pathway is highly conserved in vertebrates 30060804
2018-04-14 11:41:00 The results demonstrate that the argon plasma jet has no adverse effects on fin regeneration and embryogenesis in zebrafish, and does not interrupt the (Wnt)/beta-Catenin-signaling pathways. 28706297
2018-03-31 11:55:00 These results indicated that maternal wnt8a is dispensable for the initial dorsal determination, but cooperates with zygotic wnt8a for ventrolateral and posterior tissue formation. 29208373
2017-12-30 12:37:00 Wnt signaling balances specification of the cardiac and pharyngeal muscle fields. 28087459
2017-09-30 13:41:00 Data suggest that Wnt3, Wnt3a, and Wnt8a bind to their respective receptors (Fz8, Lrp6, and Lypd6) in ordered plasma membrane environments; ordered plasma membrane environments appear to be essential for binding of Wnt proteins to their receptor complexes and stimulation of downstream signaling activity. 28626941

名称对应

Type IDs
Synonymous wnt-8, wnt8, wnt8.1, wu:fa20e02, wu:fe05d07
Gene
UniProtKB-ID: WNT8A_DANRE
UniprotKB: P51028
UniParc: UPI0000138F75
EMBL: AY032749, U10869, BC055535
KO: dre:30122
Nucleutide sequences
EMBL-CDS: AAH55535.1, AAK70223.1, AAC59697.2
Protein sequencees
RefSeq: NP_571021.3
Others
UniRef100: UniRef100_P51028
UniRef90: UniRef90_P51028
UniRef50: UniRef50_P51028
UniGene: Dr.309

全选

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研究热度

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