| Type | Description |
|---|---|
| Definition | Spi-1 proto-oncogene b |
| Date | Results | Publications |
|---|---|---|
| 2018-05-12 10:29:00 | Data show that Spi1 is a downstream target of histone demethylase Jmjd3 (Jmjd3) during myelopoiesis. | 29378332 |
| 2017-08-19 10:29:00 | The vertical and paralleled Pu.1/Spi-b regulatory networks control the development of rostral blood island and ventral wall of dorsal aorta-borne macrophages by regulating Irf8. | 27940477 |
| 2014-05-10 14:07:00 | eaf1 has a role in suppressing foxo3b expression to modulate transcriptional activity of gata1 and spi1 in primitive hematopoiesis | 24445282 |
| 2013-04-13 10:59:00 | Our results indicate that Kzp is a critical transcriptional factor for the expression of gata2 and pu.1 to modulate primitive hematopoiesis. | 23021546 |
| 2012-08-04 11:22:00 | Runx1 is induced by high Pu.1 level and in turn transrepresses pu.1 expression, thus constituting a negative feedback loop that fashions a favorable Pu.1 level required for balanced fate commitment to neutrophils versus macrophages. | 22493295 |
| Type | IDs |
|---|---|
| Synonymous | cb1086, pu.1, pu1, sfpi1, si:by184l24.2, spi1 |
| Gene |
UniProtKB-ID:
Q8AW41_DANRE,
F1R668_DANRE,
Q78AM8_DANRE
UniprotKB:
Q8AW41,
F1R668,
Q78AM8
UniParc:
UPI00001D4B85,
UPI0000EB6EAF,
UPI0000020546
EMBL:
CT030129,
AL929252,
AL645800
Ensembl:
ENSDARG00000000767
KO:
dre:30117
|
| Nucleutide sequences |
EMBL-CDS:
CAD58735.1,
CAE48394.1
Ensembl_TRS:
ENSDART00000126831,
ENSDART00000093279,
ENSDART00000036729
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000109500,
ENSDARP00000087711,
ENSDARP00000029369
RefSeq:
NP_001315298.1,
NP_001315297.1,
XP_005168905.1,
NP_932328.2
|
| Others |
UniRef100:
UniRef100_Q8AW41,
UniRef100_Q78AM8,
UniRef100_F1R668
UniRef90:
UniRef90_Q78AM8,
UniRef90_F1R668
UniRef50:
UniRef50_G1KAS6,
UniRef50_Q6BDS1
UniGene:
Dr.34508
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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