| Type | Description |
|---|---|
| Definition | histone cluster 1 H1 family member e |
| Date | Results | Publications |
|---|---|---|
| 2020-08-12 11:13:00 | The identification of 30 patients with HIST1H1E variants has allowed the clarification of the HIST1H1E syndrome phenotype. | 31400068 |
| 2019-06-29 11:11:00 | Crystallographic studies of an histone H1.4K26me3:lysine demethylase 4A (KDM4A) complex iidicate a conserved binding geometry to that of H3K9me3. | 30156264 |
| 2016-12-17 10:05:00 | Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. | 26209608 |
| 2015-12-12 10:59:00 | This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. | 25048004 |
| 2014-08-16 12:05:00 | Histone H1.2-T165 post translational modifications are dispensable for chromatin binding and cell proliferation while the H1.4-K26 modifications are essential for proper cell cycle progression. | 24873882 |
| Type | IDs |
|---|---|
| Synonymous | H1.4, H1E, H1F4, H1s-4, RMNS, dJ221C16.5 |
| Gene |
UniProtKB-ID:
H14_HUMAN,
A3R0T8_HUMAN
UniprotKB:
P10412,
A3R0T8
UniParc:
UPI0000000DB9
EMBL:
AF531302,
EF065555,
BC099632,
BC096169,
BC096168,
AL353759,
M60748,
CH471087
Ensembl:
ENSG00000168298
KO:
hsa:3008
|
| Nucleutide sequences |
EMBL-CDS:
AAH96169.1,
AAA63187.1,
AAN06702.1,
AAH99632.1,
AAH96168.1,
EAW55534.1,
ABN72277.1
Gene_ORFName:
hCG_1645742
Ensembl_TRS:
ENST00000304218
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000307705
RefSeq:
NP_005312.1
|
| Others |
UniRef100:
UniRef100_P10412
UniRef90:
UniRef90_P10412
UniRef50:
UniRef50_P16401
UniGene:
Hs.248133
CCDS:
CCDS4586.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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