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300711 Atm

300711

Atm

ATM serine/threonine kinase

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition ATM serine/threonine kinase

研究结论

Date Results Publications
2020-10-24 14:11:00 ATM and P53 differentially regulate pancreatic beta cell survival in Ins1E cells. 32810137
2020-10-03 12:54:00 Ataxia-Telangiectasia Mutated is located in cardiac mitochondria and impacts oxidative phosphorylation. 30886180
2018-06-02 10:19:00 Expression of the ATM-Chk2 pathway increased in early stages of PAH formation, but decreased in late stages. In primary cultured PA-SMCs, KU60019 increased cell proliferation and inhibited cell apoptosis. 28894083
2018-02-24 11:40:00 pharmacological inhibition of ATM kinase (KU55933) reduced activation of ATM kinase, but not p53, suggesting that HG-mediated activation of p53 and ATM could represent independent pro-apoptotic events..these data indicate that sustained activation of Rac1-p38MAPK signaling axis leads to activation of p53 leading to beta-cell dysfunction under the duress of chronic hyperglycemic conditions 28220272
2017-09-30 10:08:00 Low ATM expression is associated with neurodegenerative disease. 28007901

名称对应

Type IDs
Gene
UniProtKB-ID: A0A0G2K3I0_RAT, D4ACL8_RAT
UniprotKB: A0A0G2K3I0, D4ACL8
UniParc: UPI0000DA2F3C, UPI000154E77C
EMBL: CH473975, AC133262, AABR07073407
Ensembl: ENSRNOG00000029773
KO: rno:300711
Nucleutide sequences
EMBL-CDS: EDL95517.1, EDL95516.1
Gene_ORFName: rCG_58300
Ensembl_TRS: ENSRNOT00000086812, ENSRNOT00000050555
Protein sequencees
Ensembl_PRO: ENSRNOP00000072646, ENSRNOP00000045529
RefSeq: XP_008764444.1, NP_001100291.1, XP_006243130.1
Others
UniRef100: UniRef100_D4ACL8, UniRef100_A0A0G2K3I0
UniRef90: UniRef90_D4ACL8, UniRef90_A0A0G2K3I0
UniRef50: UniRef50_Q13315
UniGene: Rn.214048

全选

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研究热度

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