| Type | Description |
|---|---|
| Definition | histone cluster 1 H1 family member d |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 15:25:00 | Data suggest that NPM1mut AML prognosis depends on the epigenetic silencing of the HIST1 cluster and that, among the H3K27me3 silenced histone genes, HIST1H1D plays a role in AML blast differentiation. | 31606046 |
| 2016-12-17 10:05:00 | Results show that histone H1.3, was identified only in non-neoplastic MCF-10A breast cells but not in metastatic MDA-MB-231 breast cancer cells . | 26209608 |
| 2015-07-25 11:42:00 | Histone H1 organizes and maintains an extensive protein-protein interaction network in the nucleolus required for nucleolar structure and integrity. | 25584861 |
| 2014-10-25 10:13:00 | Integration with apoptotic intermediates (via C-terminal tail interactions) may constitute a more generalized function of linker histone isoforms in apoptotic cascades. | 24525734 |
| 2014-05-10 14:02:00 | Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma. | 24435047 |
| Type | IDs |
|---|---|
| Synonymous | H1.3, H1D, H1F3, H1s-2 |
| Gene |
UniProtKB-ID:
H13_HUMAN
UniprotKB:
P16402
UniParc:
UPI0000000E14
EMBL:
BC111971,
CH471087,
AK312845,
AL031777,
AF531303,
M60747,
BC104874
Ensembl:
ENSG00000124575
KO:
hsa:3007
|
| Nucleutide sequences |
EMBL-CDS:
EAW55548.1,
AAI04875.1,
AAN06703.1,
BAG35698.1,
AAA63186.1,
AAI11972.1
Ensembl_TRS:
ENST00000244534
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000244534
RefSeq:
NP_005311.1
|
| Others |
UniRef100:
UniRef100_P16402
UniRef90:
UniRef90_P16402
UniRef50:
UniRef50_P15864
UniGene:
Hs.136857
CCDS:
CCDS4597.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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