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3006 HIST1H1C

3006

HIST1H1C

histone cluster 1 H1 family member c

protein-coding

Homo sapiens

基因描述

Type Description
Definition histone cluster 1 H1 family member c

研究结论

Date Results Publications
2019-10-12 12:39:00 these findings suggest that linker histone H1.2 functions as a physiological barrier for ATM to target the chromatin, and PARylation-mediated active H1.2 turnover is required for robust ATM activation and DNA damage repair. 29844578
2019-03-16 11:01:00 Taken together, these data provide important insights into a surprisingly complex hTR-RNA interaction network and define an unexpected non-coding RNA role for HIST1H1C in regulating telomere length homeostasis. 30355447
2019-02-09 12:24:00 The linker histone H1.2 is a novel component of nucleolar organizer regions. 29301938
2018-06-02 10:51:00 results define a network of E2F target genes as susceptible to the regulatory influence of H1.2, where H1.2 augments global association of pRb with chromatin, enhances transcriptional repression by pRb, and facilitates pRb-dependent cell-cycle arrest 28614707
2017-07-01 10:05:00 BRG1 participates in gene repression by interacting with H1.2, facilitating its deposition and stabilizing nucleosome positioning around the transcription start site. 27390128

名称对应

Type IDs
Synonymous H1.2, H1C, H1F2, H1s-1
Gene
UniProtKB-ID: H12_HUMAN
UniprotKB: P16403
UniParc: UPI0000001BD9
EMBL: X57129, AF531300, U91328, AB451385, BC002649, AK290947, CH471087, AB451259
Ensembl: ENSG00000187837
KO: hsa:3006
Nucleutide sequences
EMBL-CDS: EAW55515.1, BAF83636.1, CAA40408.1, AAN06700.1, BAG70073.1, BAG70199.1
Ensembl_TRS: ENST00000343677
Protein sequencees
Ensembl_PRO: ENSP00000339566
RefSeq: NP_005310.1
Others
UniRef100: UniRef100_P16403
UniRef90: UniRef90_P16403
UniRef50: UniRef50_P16403
UniGene: Hs.7644
CCDS: CCDS4577.1

全选

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研究热度

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