| Type | Description |
|---|---|
| Definition | proprotein convertase subtilisin/kexin type 1 inhibitor |
| Date | Results | Publications |
|---|---|---|
| 2017-11-04 12:04:00 | These analyses revealed that proSAAS KO mice show blunted acute responses to cocaine- and amphetamine (AMPH) in the open field, an absence of behavioral sensitization to cocaine, an inability to maintain sensitization to AMPH, and normal responses to the rewarding properties of cocaine in conditioned place preference. | 28881029 |
| 2014-03-15 11:58:00 | proSAAS may play a role in Alzheimer's disease pathology | 24102330 |
| 2014-02-01 11:10:00 | the effects of the neuroendocrine secretory proteins proSAAS on hIAPP fibrillation in vitro and on cytotoxicity. | 24042052 |
| 2013-05-11 10:39:00 | proSAAS as a novel down-regulated target of Pax6 | 23056534 |
| 2012-07-21 11:04:00 | ProSAAS-derived peptides are colocalized with neuropeptide Y and function as neuropeptides in the regulation of food intake | 22164236 |
| Type | IDs |
|---|---|
| Synonymous | AI848336, KEP, PEN, PEN19, PEN20, Pan3, SAAS, SAASCT, bLEN, lLEN, proSAAS |
| Gene |
UniProtKB-ID:
PCS1N_MOUSE
UniprotKB:
Q9QXV0
UniParc:
UPI00000250AB
EMBL:
BC012263,
AF181560
Ensembl:
ENSMUSG00000039278
KO:
mmu:30052
|
| Nucleutide sequences |
EMBL-CDS:
AAF22641.1,
AAH12263.1
Ensembl_TRS:
ENSMUST00000041096
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000040342
RefSeq:
NP_038920.2
|
| Others |
UniRef100:
UniRef100_Q9QXV0
UniRef90:
UniRef90_Q9QXV0
UniRef50:
UniRef50_Q9UHG2
UniGene:
Mm.4881
CCDS:
CCDS29979.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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