| Type | Description |
|---|---|
| Definition | H1 histone family member 0 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:51:00 | Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture. | 33299181 |
| 2019-08-31 11:13:00 | Histone H1 acetylation at lysine 85 (H1K85) mutation leads to genomic instability and decreased cell survival upon DNA damage. | 29982688 |
| 2019-08-03 10:46:00 | Measure the binding affinity for the prothymosin-alpha (ProTalpha)-H1.0 complex using isothermal titration calorimetry and report a KD value of (4.6 +/- 0.5) x 10(-7) M. In addition, we show that ProTalpha facilitates the formation of the H1.0-nucleosome complex in vitro. | 30430826 |
| 2017-06-24 11:36:00 | H1.X moves more rapidly than other linker histones in vivo Domain swapping between H1.0 and H1.X suggests that the globular domain (GD) and C-terminal domain (CTD) of H1.X independently contribute to the dynamic behavior of H1.X. | 27528617 |
| 2017-04-01 12:41:00 | this study shows that dynamic epigenetic states defined by the linker histone H1.0 determine which cells within a tumor can sustain the long-term cancer growth. | 27708074 |
| Type | IDs |
|---|---|
| Synonymous | H10, H1FV |
| Gene |
UniProtKB-ID:
H10_HUMAN
UniprotKB:
P07305
UniParc:
UPI0000161F7B,
UPI00017A7BA4
EMBL:
Z97630,
CR542220,
AK312583,
BC029046,
BC000145,
X03473,
CH471095,
AK299209,
CR456502
Ensembl:
ENSG00000189060
KO:
hsa:3005
|
| Nucleutide sequences |
EMBL-CDS:
CAG30388.1,
AAH00145.1,
AAH29046.1,
EAW60188.1,
CAG47016.1,
BAG61248.1,
CAA27190.1,
BAG35477.1
Ensembl_TRS:
ENST00000340857
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000344504
RefSeq:
NP_005309.1
|
| Others |
UniRef100:
UniRef100_P07305
UniRef90:
UniRef90_P07305
UniRef50:
UniRef50_P07305
UniGene:
Hs.745024
CCDS:
CCDS13956.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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