| Type | Description |
|---|---|
| Definition | granzyme M |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 10:16:00 | Granzyme B and granzyme M cleave IE1 after Asp398 and Leu414, respectively, likely resulting in IE1 aberrant cellular localization. | 32282833 |
| 2017-10-28 13:40:00 | GzMM has a critical role during early stages of inflammation in ulcerative colitis; in its absence colonic inflammation is enhanced. | 27441655 |
| 2017-05-13 16:50:00 | We also report that TNFalpha induces the attachment of Met1-linked Ub chains directly to TNF receptor 1, which do not seem to be attached covalently to Lys63-linked or other types of ubiquitin chain. | 27133719 |
| 2014-03-15 12:44:00 | Granzym M may be important in regulating HCMV latency and reactivation in SCT patients. | 24316590 |
| 2013-08-31 10:18:00 | GrM is expressed in HCMV-specific CD8thorn T cells and cleaves host cell protein hnRNP K in the presence of RNA. | 23099853 |
| Type | IDs |
|---|---|
| Synonymous | LMET1, MET1 |
| Gene |
UniProtKB-ID:
GRAM_HUMAN
UniprotKB:
P51124
UniParc:
UPI000013D531
EMBL:
L36936,
L23134,
BC025701,
AC011556,
L36922
Ensembl:
ENSG00000197540
KO:
hsa:3004
|
| Nucleutide sequences |
EMBL-CDS:
AAA57262.1,
AAA57257.1,
AAA59582.1,
AAH25701.1
Ensembl_TRS:
ENST00000264553
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000264553
RefSeq:
NP_001245280.2,
NP_005308.2
|
| Others |
UniRef100:
UniRef100_P51124
UniRef90:
UniRef90_P51124
UniRef50:
UniRef50_P51124
UniGene:
Hs.465511
CCDS:
CCDS12031.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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