| Type | Description |
|---|---|
| Definition | granzyme K |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 11:31:00 | We here provide ex vivo evidence that CCR5highGZMK+CD4+ effector memory T cells are involved in immune surveillance during homeostasis, but could also play a role in pathology | 31563951 |
| 2020-04-04 11:52:00 | GzmK induced IL-6 expression in keratinocytes and skin fibroblasts that was dependent on PAR-1 activation. Re-epithelialization showed the greatest degree of improvement of all healing parameters, suggesting that keratinocytes are sensitive to GzmK-mediated proteolysis. In support, keratinocytes, but not skin fibroblasts, exposed to GzmK showed impaired wound healing in vitro | 30395844 |
| 2017-06-24 12:30:00 | Extracellular granzyme K mediates endothelial activation through the cleavage of PAR-1. | 26936634 |
| 2017-04-08 12:22:00 | Carbamate pesticides significantly reduced the intracellular levels of perforin, GrA, GrB, Gr3/K, and GRN in NK-92CI cells. | 25921628 |
| 2015-10-31 11:25:00 | Data indicate N-terminomics on the human and mouse granzymes A and K by combined fractional diagonal chromatography (COFRADIC). | 25383893 |
| Type | IDs |
|---|---|
| Synonymous | TRYP2 |
| Gene |
UniProtKB-ID:
GRAK_HUMAN
UniprotKB:
P49863
UniParc:
UPI0000001C46
EMBL:
CH471123,
AK312074,
BC035802,
U26174,
U35237
Ensembl:
ENSG00000113088
KO:
hsa:3003
|
| Nucleutide sequences |
EMBL-CDS:
BAG35010.1,
AAA74578.1,
AAA79063.1,
EAW54899.1,
AAH35802.1
Ensembl_TRS:
ENST00000231009
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000231009
RefSeq:
NP_002095.1
|
| Others |
UniRef100:
UniRef100_P49863
UniRef90:
UniRef90_P49863
UniRef50:
UniRef50_P49863
UniGene:
Hs.277937
CCDS:
CCDS3964.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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