| Type | Description |
|---|---|
| Definition | T cell leukemia homeobox 3 |
| Date | Results | Publications |
|---|---|---|
| 2016-11-12 11:07:00 | Egyptian T-cell acute lymphoblastic leukemia cases seemed to have a different genetic pattern compared to other populations, with a lower incidence of TLX3/HOX11L2 and SIL/TAL but a higher incidence of NKX2-5 expression than recorded in Western countries | 24571118 |
| 2016-10-29 10:50:00 | Immunophenotyping with CD135 and CD117 predicts the FLT3, IL-7R and TLX3 gene mutations in childhood T-cell acute leukemia. | 26852660 |
| 2015-01-03 10:38:00 | Studies suggest that homeobox protein TLX3 expression is not an indicator for the prognosis of pediatric T cell acute lymphocytic leukemia (T-ALL). | 24997618 |
| 2012-06-23 11:59:00 | these results place TLX1 and TLX3 at the top of an oncogenic transcriptional network controlling leukemia development, and identify RUNX1 as a tumor-suppressor gene in T-ALL | 22366949 |
| 2012-06-23 10:47:00 | The cortical thymic maturation arrest in T-lineage Acute lymphoblastic leukemias (ALLs) that overexpress TLX1 or TLX3 is due to binding of TLX1/TLX3 to ETS1. | 22516263 |
| Type | IDs |
|---|---|
| Synonymous | HOX11L2, RNX |
| Gene |
UniProtKB-ID:
TLX3_HUMAN
UniprotKB:
O43711
UniParc:
UPI000013E3AA
EMBL:
AJ223798,
BC017291,
AJ223799,
AJ223800
Ensembl:
ENSG00000164438
KO:
hsa:30012
|
| Nucleutide sequences |
EMBL-CDS:
CAA11550.1,
AAH17291.1
Ensembl_TRS:
ENST00000296921
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000296921
RefSeq:
NP_066305.2
|
| Others |
UniRef100:
UniRef100_O43711
UniRef90:
UniRef90_O43711
UniRef50:
UniRef50_O43711
UniGene:
Hs.249125
CCDS:
CCDS34288.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员