| Type | Description |
|---|---|
| Definition | EGF containing fibulin extracellular matrix protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:49:00 | EFEMP2 indicates assembly of M0 macrophage and more malignant phenotypes of glioma. | 32396873 |
| 2019-11-30 11:54:00 | These results may explain the changes in protease cleavage sites, reduced secretion and impaired extracellular assembly of the E126K and D203A fibulin-4 mutants and provide further insight into understanding the molecular basis of the associated clinical phenotypes. | 31125616 |
| 2019-11-16 11:13:00 | These results are consistent with a role of FBLN2 in mammary epithelial basement membrane stability, and that its down-regulation in breast cancer is associated with loss of the basement membrane and early invasion. | 30237579 |
| 2018-02-10 10:42:00 | different mutations in the fibulin-4 gene result in different molecular defects affecting secretion rates, protein stability, LOX-induced cross-linking, or binding to other ECM components and molecules of the TGF-beta pathway. | 27339457 |
| 2017-09-23 10:46:00 | the expression of fibulin-4 was negatively correlated with the malignant phenotype of endometrial cancer cells. Fibulin-4 may have the ability to suppress endometrial cancer cell invasion and proliferation | 28177909 |
| Type | IDs |
|---|---|
| Synonymous | ARCL1B, FBLN4, MBP1, UPH1 |
| Gene |
UniProtKB-ID:
FBLN4_HUMAN,
A0A024R5G1_HUMAN,
Q9H3D5_HUMAN
UniprotKB:
O95967,
A0A024R5G1,
Q9H3D5
UniParc:
UPI00000712BB,
UPI000013EC97
EMBL:
AF124486,
AK000980,
AK292079,
AK075453,
AF109121,
CH471076,
AY358899,
BC010456,
AJ132819,
AF093119,
AP001201
Ensembl:
ENSG00000172638
KO:
hsa:30008
|
| Nucleutide sequences |
EMBL-CDS:
BAG50843.1,
AAF65188.1,
BAG52143.1,
AAQ89258.1,
AAH10456.1,
AAC62108.1,
BAF84768.1,
CAA10791.2,
EAW74456.1,
EAW74459.1,
EAW74462.1,
EAW74461.1,
EAW74458.1,
EAW74455.1,
EAW74457.1,
AAG45245.1
Gene_ORFName:
UNQ200/PRO226,
hCG_2019682
Ensembl_TRS:
ENST00000307998,
ENST00000531972
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000435295,
ENSP00000309953
RefSeq:
NP_058634.4
|
| Others |
UniRef100:
UniRef100_O95967,
UniRef100_Q9H3D5
UniRef90:
UniRef90_O95967
UniRef50:
UniRef50_O95967
UniGene:
Hs.731454
CCDS:
CCDS8116.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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