| Type | Description |
|---|---|
| Definition | endoplasmic reticulum oxidoreductase 1 alpha |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:57:00 | Non-native proteins inhibit the ER oxidoreductin 1 (Ero1)-protein disulfide-isomerase relay when protein folding capacity is exceeded. | 32102847 |
| 2019-12-14 10:24:00 | ERO1-Lalpha promotes hepatocellular carcinoma metastasis and angiogenesis through the pathway. | 30377291 |
| 2019-11-30 12:37:00 | Data found that ERO1alpha expression increased under chronic hypoxia. Our results show that ERO1alpha was hypoxia-induced in all the tested cancer cell lines. | 31142270 |
| 2019-10-12 13:12:00 | Mechanism analysis suggested that ERO1L promoted many tumor-associated signaling pathways, especially the Wnt/catenin pathway; it could activate the Wnt/catenin pathway and upregulate the targets of the Wnt/catenin pathway. | 30076651 |
| 2019-07-13 10:33:00 | Mutation of Val101 of Ero1 alpha results in a reduced Endoplasmic reticulum , retarded oxidative protein folding and decreased H2O2 levels in the Endoplasmic reticulum of cervical cancer cells and further impairs cell migration, invasion, and tumor growth. | 30826359 |
| Type | IDs |
|---|---|
| Synonymous | ERO1-L, ERO1-L-alpha, ERO1-alpha, ERO1L, ERO1LA, Ero1alpha |
| Gene |
UniProtKB-ID:
ERO1A_HUMAN
UniprotKB:
Q96HE7
UniParc:
UPI000004BA63
EMBL:
AL133453,
AF123887,
AY358463,
BC008674,
AK292839,
BC012941,
AF081886
Ensembl:
ENSG00000197930
KO:
hsa:30001
|
| Nucleutide sequences |
EMBL-CDS:
AAH08674.1,
AAQ88828.1,
AAH12941.1,
AAF06104.1,
BAF85528.1,
AAF35260.1
Gene_ORFName:
UNQ434/PRO865
Ensembl_TRS:
ENST00000395686
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000379042
RefSeq:
XP_024305322.1,
NP_001369393.1,
NP_001369397.1,
NP_001369402.1,
NP_001369401.1,
NP_001369405.1,
NP_001369403.1,
NP_001369396.1,
NP_001369395.1,
NP_001369394.1,
NP_055399.1,
NP_001369399.1,
NP_001369398.1,
NP_001369400.1,
NP_001369404.1
|
| Others |
UniRef100:
UniRef100_Q96HE7
UniRef90:
UniRef90_Q96HE7
UniRef50:
UniRef50_Q96HE7
UniGene:
Hs.592304
CCDS:
CCDS9709.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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