| Type | Description |
|---|---|
| Definition | NOP53 ribosome biogenesis factor |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:56:00 | Downregulation of NOP53 Ribosome Biogenesis Factor Leads to Abnormal Nuclear Division and Chromosomal Instability in Human Cervical | 30421090 |
| 2020-03-14 11:36:00 | Germline variant p. Asp31His was present in all affected members in three families with familial non-medullary thyroid cancer. NOP53 is likely a low-penetrant gene implicated in FNMTC. | 31703244 |
| 2018-10-06 11:24:00 | Blocking cytoplasmic translocation of nucleolar protein NOP53 by deleting its nuclear export sequence abrogated its support of viral replication. Recombinant N3-T protein, containing NOP53 residues 330-432 and a human immunodeficiency virus-derived cell-penetrating Tat peptide, attenuated the expression of IFN-beta; and IFN-stimulated genes, as well as decreased the phosphorylation of interferon regulatory factor3. | 29677136 |
| 2018-07-07 10:05:00 | The findings of this study suggest that disruption of PICT-1 protein expression and codon 389 polymorphism can contribute to the pathogenesis or neoplastic progression of endometrial cancer. | 29617699 |
| 2018-06-30 10:08:00 | The study presented evidence that viral infection induced translocation of GLTSCR2 from nucleus to cytoplasm, and cytoplasmic translocation enabled GLTSCR2 to effectively attenuate IFN-beta and support viral replication; however, viral infection did not result in elevating GLTSCR2 in cells. | 27824081 |
| Type | IDs |
|---|---|
| Synonymous | GLTSCR2, PICT-1, PICT1 |
| Gene |
UniProtKB-ID:
NOP53_HUMAN
UniprotKB:
Q9NZM5
UniParc:
UPI0000054111
EMBL:
AF296124,
BC010095,
AF182076,
AL359335,
BC006311,
AL359336,
BC004229,
AL122063
Ensembl:
ENSG00000105373
KO:
hsa:29997
|
| Nucleutide sequences |
EMBL-CDS:
CAB94787.1,
CAB59242.1,
AAH04229.2,
AAF62873.1,
CAB94786.1,
AAG30413.1,
AAH06311.1,
AAH10095.1
Ensembl_TRS:
ENST00000246802
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000246802
RefSeq:
NP_056525.2
|
| Others |
UniRef100:
UniRef100_Q9NZM5
UniRef90:
UniRef90_Q9NZM5
UniRef50:
UniRef50_Q9NZM5
UniGene:
Hs.421907
CCDS:
CCDS12705.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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