Type | Description |
---|---|
Definition | bromodomain adjacent to zinc finger domain 2B |
Date | Results | Publications |
---|---|---|
2020-05-16 10:22:00 | Study identified BAZ2B as a major interactant of small hepatitis delta virus (HDV) antigen (S-HDAg) in human hepatocytes. BAZ2B bromodomain, which generally binds the K14acXXR motif in histone H3-tail, recognizes the same K72acXXR motif in S-HDAg. S-HDAg mimics histone H3 acetylation to recruit BAZ2B-associated remodeling factor complexes and RNA Pol II on the HDV ribonucleoproteins to sustain HDV replication. | 31964889 |
2020-05-02 11:39:00 | Synergistic inhibition of BDs encoded in BAZ2A/B, BRD9, and BET proteins induces apoptosis of triple-negative breast cancer (TNBC) by a combinatorial suppression of ribosomal DNA transcription and ETS-regulated genes. | 31000582 |
2017-11-04 12:38:00 | Phosphorylation, acetylation, or poly(ADP-ribosyl)ation of the linker residues may therefore act as a cellular mechanism to transiently tune BAZ2B histone-binding affinity. | 28864776 |
2017-06-24 11:23:00 | Data suggest that binding of helical tail of histone 3 (H3) with PHD ('plant homeodomain') fingers of BAZ2A or BAZ2B (bromodomain adjacent to zinc finger domain 2A or 2B) requires molecular recognition of secondary structure motifs within H3 tail and could represent an additional layer of regulation in epigenetic processes. | 28341809 |
2010-09-15 22:05:00 | Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | 20802025 |
Type | IDs |
---|---|
Synonymous | WALp4 |
Gene |
UniProtKB-ID:
BAZ2B_HUMAN
UniprotKB:
Q9UIF8
UniParc:
UPI00019B21DE,
UPI000013E1D5,
UPI00019B21DF,
UPI0000E5A28F,
UPI0000D74C4A
EMBL:
AB040909,
BC012576,
AL080173,
AL834381,
AK027612,
AB032255,
CH471058
Ensembl:
ENSG00000123636
KO:
hsa:29994
|
Nucleutide sequences |
EMBL-CDS:
CAD39044.2,
EAX11404.1,
BAB55231.1,
BAA96000.2,
AAH12576.1,
BAA89212.1,
EAX11405.1,
CAB45759.1,
EAX11407.1
Ensembl_TRS:
ENST00000392782,
ENST00000392783
|
Protein sequencees |
Ensembl_PRO:
ENSP00000376533,
ENSP00000376534
RefSeq:
XP_016859420.1,
XP_011509356.1,
XP_016859413.1,
XP_024308596.1,
XP_016859419.1,
XP_011509355.1,
XP_011509349.1,
XP_011509347.1,
XP_016859415.1,
XP_011509353.1,
XP_016859417.1,
XP_016859425.1,
XP_016859412.1,
XP_011509354.1,
XP_011509341.1,
XP_016859423.1,
XP_011509345.1,
XP_011509358.1,
NP_001276904.1,
XP_016859426.1,
NP_038478.2,
XP_016859410.1,
XP_024308595.1,
XP_016859409.1,
XP_016859414.1,
XP_011509350.1,
NP_001316786.1,
XP_024308593.1,
XP_011509352.1,
XP_011509344.1,
XP_024308594.1,
XP_005246545.2,
XP_011509340.1,
XP_005246549.2,
XP_005246546.2,
NP_001316787.1,
XP_016859422.1,
XP_011509346.1,
XP_016859411.1,
XP_016859424.1,
XP_024308597.1
|
Others |
UniRef100:
UniRef100_Q9UIF8
UniRef90:
UniRef90_Q9UIF8
UniRef50:
UniRef50_Q9UIF8
UniGene:
Hs.470369
CCDS:
CCDS74594.1,
CCDS2209.2
|
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Refseq |
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