| Type | Description |
|---|---|
| Definition | paired immunoglobin like type 2 receptor alpha |
| Date | Results | Publications |
|---|---|---|
| 2020-01-25 10:43:00 | Herpes simplex virus type 1 IgG are increased in Alzheimer's disease patients with the protective R78 PILRA genotype. | 31297637 |
| 2019-11-09 10:36:00 | Exome-wide burden analysis revealed significant burden of variants in PILRA in patients with late-onset Alzheimer's disease | 29181857 |
| 2019-02-09 13:09:00 | We propose that PILRA G78R protects individuals from Alzheimer's disease risk via reduced inhibitory signaling in microglia and reduced microglial infection during HSV-1 recurrence. | 30388101 |
| 2018-11-20 14:17:00 | Data suggest that, although PILRA exhibits essentially the same recognition of different glycopeptides, slight modifications of linker sugar cause significant changes in a wide area of the binding interface, resulting in a reduction of binding affinity; analogs/fragments of gpb were used in these studies. (PILRA = paired immunoglobin like type 2 receptor alpha; gpb = envelope glycoprotein B, Herpes simplex virus type 1) | 29046357 |
| 2018-01-13 11:20:00 | The interaction of NK cells with PILRalpha expressing targets lead to elevated IFNgamma secretion and cytotoxicity. In conclusion, PILRalpha is a novel NK activating ligand which binds and activates an unknown NK receptor expressed on a unique NK cell subset. | 27029068 |
| Type | IDs |
|---|---|
| Synonymous | FDF03 |
| Gene |
UniProtKB-ID:
PILRA_HUMAN
UniprotKB:
Q9UKJ1
UniParc:
UPI0001D14770,
UPI0000190FB2,
UPI000013C61C,
UPI0000190FB1
EMBL:
AJ400843,
AJ400842,
BC017812,
AJ400841,
AF161080,
AC005071
Ensembl:
ENSG00000085514
KO:
hsa:29992
|
| Nucleutide sequences |
EMBL-CDS:
CAC01615.1,
AAD52964.1,
AAH17812.1,
CAC01614.1,
CAC01613.1
Ensembl_TRS:
ENST00000394000,
ENST00000198536,
ENST00000350573
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000198536,
ENSP00000340109,
ENSP00000377569
RefSeq:
XP_024302507.1,
NP_840056.1,
NP_038467.2,
NP_840057.1
|
| Others |
UniRef100:
UniRef100_Q9UKJ1
UniRef90:
UniRef90_Q9UKJ1
UniRef50:
UniRef50_Q9UKJ1
UniGene:
Hs.444407
CCDS:
CCDS5692.1,
CCDS47660.1,
CCDS5691.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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