| Type | Description |
|---|---|
| Definition | granzyme H |
| Date | Results | Publications |
|---|---|---|
| 2013-08-31 11:11:00 | Granzyme H did directly process DFF45, potentially leading to DNA damage. | 23352961 |
| 2013-03-30 11:21:00 | Upon reactive center loop cleavage at Phe-343,SERPINB1 covalently complexes with GzmH. SERPINB1 overexpression suppresses GzmH- or LAK cell-mediated cytotoxicity. Crystal structures show possible conformational changes in GzmH for the suicide inhibition. | 23269243 |
| 2012-02-25 10:54:00 | An unusual RKR motif (Arg39-Lys40-Arg41), conserved only in GzmH, helps define the S3' and S4' binding regions, indicating the preference for acidic residues at the P3' and P4' sites. | 22156497 |
| 2012-02-25 10:07:00 | GzmH suppresses viral replication through association with the hepatitis B virus x protein. | 22156339 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20800603 |
| Type | IDs |
|---|---|
| Synonymous | CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2 |
| Gene |
UniProtKB-ID:
GRAH_HUMAN
UniprotKB:
P20718
UniParc:
UPI0000D623E4,
UPI0000242BD4,
UPI00000012B3
EMBL:
CH471078,
AL136018,
M57888,
M72150,
BC027974,
M36118,
J02907,
AY232658,
AY232657
Ensembl:
ENSG00000100450
KO:
hsa:2999
|
| Nucleutide sequences |
EMBL-CDS:
AAA03248.1,
AAP70247.1,
AAP70248.1,
AAA76859.1,
AAH27974.1,
EAW66004.1,
AAA74885.1,
AAA03514.1
Ensembl_TRS:
ENST00000382548,
ENST00000216338
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000371988,
ENSP00000216338
RefSeq:
XP_011534985.1,
NP_001257709.1,
NP_219491.1,
NP_001257710.1
|
| Others |
UniRef100:
UniRef100_P20718
UniRef90:
UniRef90_P20718
UniRef50:
UniRef50_P20718
UniGene:
Hs.348264
CCDS:
CCDS9632.1,
CCDS59243.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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