| Type | Description |
|---|---|
| Definition | leucine rich repeat containing G protein coupled receptor 5 |
| Date | Results | Publications |
|---|---|---|
| 2018-07-21 11:52:00 | IL-6 expression increased in all groups compared to control. Lgr5 expression was up-regulated in cells exposed to a single stressor, but down-regulated when multiple stressors were administered. | 29018960 |
| 2017-04-08 11:28:00 | that Leucine-rich repeat-containing G-protein coupled receptor 5might be of great significance in CNS pathophysiology after spinal cord injury | 27339869 |
| 2016-10-01 11:18:00 | Report targeting LGR5+ tumor stem cells with an antibody-drug conjugate as effective treatment for colon cancer. | 26582901 |
| 2013-06-15 10:59:00 | Results support LGR-5 as a putative neoplastic stem cell marker in colonic tumors co-expressing nuclear beta-catenin. | 23374535 |
| Type | IDs |
|---|---|
| Synonymous | Gpr49 |
| Gene |
UniProtKB-ID:
LGR5_RAT
UniprotKB:
D4AC13
UniParc:
UPI000018206F
EMBL:
AABR06049743,
AABR06049742,
AABR06049740,
AABR06049744,
AABR06049741,
CH473960
Ensembl:
ENSRNOG00000004221
KO:
rno:299802
|
| Nucleutide sequences |
EMBL-CDS:
EDM16685.1
Ensembl_TRS:
ENSRNOT00000005814
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000005814
RefSeq:
XP_017450229.1,
NP_001100254.1
|
| Others |
UniRef100:
UniRef100_D4AC13
UniRef90:
UniRef90_Q9Z1P4
UniRef50:
UniRef50_O75473
UniGene:
Rn.214063
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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