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29979 UBQLN1

29979

UBQLN1

ubiquilin 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition ubiquilin 1

研究结论

Date Results Publications
2019-10-19 12:31:00 finding suggests that there is a dynamic interplay between RRM2 and the NS5B-hPLIC1 complex that has an important function in HCV replication. Together, these results identify a role of host RRM2 in viral RNA replication. 30755480
2018-10-06 10:52:00 The genome of Drosophila contains a single UBQLN homolog (dUbqn) that shows high similarity to UBQLN1 and UBQLN2; therefore, the fly is a useful model for characterizing the role of UBQLN in vivo in neurological disorders affecting locomotion and learning abilities. 29247619
2018-06-16 10:52:00 Thus, UBQLN1 plays an important role in clearing mislocalized mitochondrial proteins upon cell stimulation, and its absence leads to suppression of protein synthesis and cell cycle arrest. 28933694
2018-04-14 10:38:00 UBQLN1 variant was not associated with the risk of Alzheimer's disease. 28719358
2017-12-30 11:13:00 The STI and UBA Domains of UBQLN1 Are Critical Determinants of Substrate Interaction and Proteostasis. 28075048

名称对应

Type IDs
Synonymous DA41, DSK2, PLIC-1, UBQN, XDRP1
Gene
UniProtKB-ID: UBQL1_HUMAN, A0A024R258_HUMAN
UniprotKB: Q9UMX0, A0A024R258
UniParc: UPI00063BD2BD, UPI00063BD2C2, UPI0000038DA1, UPI000013E45A
EMBL: AB035275, AL354920, HM005532, AL136643, AF293384, BC039294, AF176069, AK074535, CH471089, BC010066
Ensembl: ENSG00000135018
KO: hsa:29979
Nucleutide sequences
EMBL-CDS: BAB20436.1, EAW62659.1, EAW62661.1, AAH10066.1, CAB66578.1, AAH39294.1, AAG02473.1, AEE61129.1, EAW62664.1, AAD49751.3, EAW62663.1
Gene_ORFName: hCG_27739
Ensembl_TRS: ENST00000376395, ENST00000257468
Protein sequencees
Ensembl_PRO: ENSP00000365576, ENSP00000257468
RefSeq: NP_444295.1, NP_038466.2, XP_005252005.1
Others
UniRef100: UniRef100_Q9UMX0, UniRef100_A0A024R258
UniRef90: UniRef90_Q9UMX0, UniRef90_A0A287B231
UniRef50: UniRef50_Q9UHD9, UniRef50_Q9UMX0
UniGene: Hs.9589
CCDS: CCDS6663.1, CCDS6664.1

全选

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