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2997 GYS1

2997

GYS1

glycogen synthase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition glycogen synthase 1

研究结论

Date Results Publications
2017-10-21 12:14:00 Insulin-stimulated glycogen synthase (GS) activity was completely ablated during hyperinsulinemic hypoglycemia, and catecholamine signaling via cAMP-dependent protein kinase and phosphorylation of inhibiting sites on GS all increased. 28596236
2015-12-05 10:34:00 Overexpression of GYS1, MIF, and MYC is associated with adverse outcome and poor response to azacitidine in myelodysplastic syndromes and acute myeloid leukemia 25487600
2015-10-03 11:19:00 over-expression of muscle glycogen synthase (MGS)was detected in diabetic human kidney 25371328
2015-10-03 10:23:00 High glycogen synthase 1 expression is associated with myeloid leukemia. 25703587
2013-05-11 12:24:00 Data suggest that although COOH-terminal dephosphorylation is likely necessary for GS activation, protein kinase Akt-2- (Akt2)-dependent NH2-terminal dephosphorylation is site for "fine-tuning" insulin-mediated GS activation in skeletal muscle. 23321478

名称对应

Type IDs
Synonymous GSY, GYS
Gene
UniProtKB-ID: GYS1_HUMAN
UniprotKB: P13807
UniParc: UPI0000000C44, UPI000007098C
EMBL: AC008687, AC026803, Z33627, Z33629, BC002617, AC098792, BC003182, Z33622, J04501, Z33623, Z33628, Z33609, Z33625, Z33610, Z33631, CH471177, BC007688, Z33633, Z33624, Z33630, U32573, Z33626
Ensembl: ENSG00000104812
KO: hsa:2997
Nucleutide sequences
EMBL-CDS: AAH02617.1, AAB60385.1, AAA88046.1, AAH07688.1, CAA83916.1, AAH03182.1, EAW52424.1
Ensembl_TRS: ENST00000323798, ENST00000263276
Protein sequencees
Ensembl_PRO: ENSP00000263276, ENSP00000317904
RefSeq: NP_001155059.1, NP_002094.2
Others
UniRef100: UniRef100_P13807
UniRef90: UniRef90_P13807
UniRef50: UniRef50_P13807
UniGene: Hs.386225
CCDS: CCDS12747.1, CCDS54292.1

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