Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.

Immunity     Ricardo Rajsbaum , Gijs A Versteeg , Sonja Schmid , Ana M Maestre , Alan Belicha-Villanueva , Carles Martínez-Romero , Jenish R Patel , Juliet Morrison , Giuseppe Pisanelli , Lisa Miorin , Maudry Laurent-Rolle , Hong M Moulton , David A Stein , Ana Fernandez-Sesma , Benjamin R tenOever , Adolfo García-Sastre

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.

Brief. Bioinformatics     Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas

Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrate.

Mol Cell     Kenneth Wu , Jordan Kovacev , Zhen-Qiang Pan

The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

J Biol Chem     Yael David , Tamar Ziv , Arie Admon , Ami Navon

Gene and alternative splicing annotation with AIR.

Genome Res.     Liliana Florea , Valentina Di Francesco , Jason Miller , Russell Turner , Alison Yao , Michael Harris , Brian Walenz , Clark Mobarry , Gennady V Merkulov , Rosane Charlab , Ian Dew , Zuoming Deng , Sorin Istrail , Peter Li , Granger Sutton

Differential regulation of components of the ubiquitin-proteasome pathway during lens cell differentiation.

Invest. Ophthalmol. Vis. Sci.     Weimin Guo , Fu Shang , Qing Liu , Lyudmila Urim , Judith West-Mays , Allen Taylor

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.

Proc. Natl. Acad. Sci. U.S.A.     Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team

Proteasomal inhibition-induced inclusion formation and death in cortical neurons require transcription and ubiquitination.

Mol. Cell. Neurosci.     Hardy J Rideout , Leonidas Stefanis

Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis.

Mol Cell Biol     D Pati , M L Meistrich , S E Plon

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.

Mol. Cell     T Ohta , J J Michel , A J Schottelius , Y Xiong