| Type | Description |
|---|---|
| Definition | mitochondrial rRNA methyltransferase 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-03-24 10:16:00 | Targeted exome sequencing of genes encoding the mitochondrial proteome identified a damaging mutation, c.567 G > A, affecting a highly conserved amino acid residue (p.Gly189Arg) of the MRM2 protein. Our findings establish that defective MRM2 causes a MELAS-like phenotype, and suggests the genetic screening of the MRM2 gene in patients with a m.3243 A > G negative MELAS-like presentation. | 28973171 |
| 2017-09-30 12:34:00 | miR-542-3p functions as a suppressor gene by targeting and upregulating FTSJ2, thus inhibiting the malignancy of non-small cell lung cancer cells | 28866101 |
| 2015-05-30 11:38:00 | MRM2 and MRM3 are human mitochondrial methyltransferases involved in the modification of 16S rRNA and are important factors for the biogenesis and function of the large subunit of the mitochondrial ribosome. | 25009282 |
| 2015-01-31 11:51:00 | Data show that 2'-O-methyltransferases MRM1, MRM2, and RNMTL1 are responsible for modification of large subunit rRNA at residues G1145, U1369, and G1370, respectively. | 25074936 |
| 2014-11-08 11:15:00 | FTSJ2 possesses suppressive effects on the invasion and migration of cancer cells. | 24595062 |
| Type | IDs |
|---|---|
| Synonymous | FJH1, FTSJ2, HEL97, RRMJ2 |
| Gene |
UniProtKB-ID:
MRM2_HUMAN,
V9HWJ9_HUMAN
UniprotKB:
Q9UI43,
V9HWJ9
UniParc:
UPI00000373C0
EMBL:
EU794658,
AF093415,
BC114514,
CH471144
Ensembl:
ENSG00000122687
KO:
hsa:29960
|
| Nucleutide sequences |
EMBL-CDS:
AAF22488.1,
AAI14515.1,
ACJ13712.1,
EAW87223.1,
EAW87224.1
Gene_ORFName:
hCG_17134
Ensembl_TRS:
ENST00000242257,
ENST00000440306
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000242257,
ENSP00000392343
RefSeq:
NP_037525.1
|
| Others |
UniRef100:
UniRef100_Q9UI43
UniRef90:
UniRef90_Q9UI43
UniRef50:
UniRef50_Q9UI43
UniGene:
Hs.279877
CCDS:
CCDS5328.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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