PDZRN4 - PDZ domain containing ring finger 4-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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29951 PDZRN4

基因描述

Type	Description
Definition	PDZ domain containing ring finger 4

研究结论

Date	Results	Publications
2016-08-27 11:57:00	Results showed that PDZRN4 might be a potential tumour suppressor gene and had anti-proliferative effect on hepatocellular carcinoma cell proliferation.	26486104
2010-12-05 22:08:00	Observational study of gene-disease association. (HuGE Navigator)	20944657

名称对应

Type	IDs
Synonymous	LNX4, SAMCAP3L
Gene	UniProtKB-ID: PZRN4_HUMAN, B4DGD1_HUMAN UniprotKB: Q6ZMN7, B4DGD1 UniParc: UPI0000D621D0, UPI00017A6F43, UPI000041C287, UPI00001FC019 EMBL: BC093744, BX640695, AC090531, AK131554, AL133067, BC093746, BC040922, AK294535, AC021651 Ensembl: ENSG00000165966 KO: hsa:29951
Nucleutide sequences	EMBL-CDS: AAH40922.1, AAH93746.2, BAD18688.1, CAE45818.2, AAH93744.1, CAB61390.3, BAG57742.1 Ensembl_TRS: ENST00000539469, ENST00000298919, ENST00000402685
Protein sequencees	Ensembl_PRO: ENSP00000384197, ENSP00000439990, ENSP00000298919 RefSeq: NP_037509.3, NP_001158067.1
Others	UniRef100: UniRef100_Q6ZMN7, UniRef100_B4DGD1 UniRef90: UniRef90_Q6ZMN7, UniRef90_Q6ZMN7-2 UniRef50: UniRef50_Q6ZMN7-2, UniRef50_Q6ZMN7 UniGene: Hs.380044 CCDS: CCDS53777.1, CCDS8739.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Ensembl: {{protein.nucleotideEnsembl}}

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Location

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Pubmed编号	文献信息	发表日期	相关基因
30726710	Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation. J. Mol. Biol. GergÅ GÃ³gl , BeÃ¡ta Biri-KovÃ¡cs , Fabien Durbesson , Pau Jane , Yves Nomine , Camille Kostmann , ViktÃ³ria Bilics , MÃ¡rton Simon , Attila RemÃ©nyi , Renaud Vincentelli , Gilles Trave , LÃ¡szlÃ³ Nyitray	2019-03-15	-
28786561	Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system. FEBS J. Juline Poirson , Elise Biquand , Marie-Laure Straub , Patricia Cassonnet , Yves NominÃ© , Louis Jones , Sylvie van der Werf , Gilles TravÃ© , Katia Zanier , Yves Jacob , Caroline Demeret , Murielle Masson	2017-10-01	-
26486104	PDZRN4 acts as a suppressor of cell proliferation in human liver cancer cell lines. Cell Biochem. Funct. Taotao Hu , Hong Yang , Ze-Guang Han	2015-10-01	-
26053890	Quantifying domain-ligand affinities and specificities by high-throughput holdup assay. Nat. Methods Renaud Vincentelli , Katja Luck , Juline Poirson , Jolanta Polanowska , Julie Abdat , Marilyne BlÃ©mont , Jeremy Turchetto , FranÃ§ois Iv , Kevin Ricquier , Marie-Laure Straub , Anne Forster , Patricia Cassonnet , Jean-Paul Borg , Yves Jacob , Murielle Masson , Yves NominÃ© , JÃ©rÃ´me Reboul , Nicolas Wolff , Sebastian Charbonnier , Gilles TravÃ©	2015-08-01	-
24986923	A genome-wide association study identifies susceptibility loci of silica-related pneumoconiosis in Han Chinese. Hum. Mol. Genet. Minjie Chu , Xiaoming Ji , Weihong Chen , Ruyang Zhang , Chongqi Sun , Ting Wang , Chen Luo , Jianhang Gong , Meng Zhu , Jingjing Fan , Zhiguo Hou , Juncheng Dai , Guangfu Jin , Tangchun Wu , Feng Chen , Zhibin Hu , Chunhui Ni , Hongbing Shen	2014-12-01	CPSF6, CNTN1, CPM, PDZRN4, LAMB1, MDM2
22889411	Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase. J. Proteome Res. Zhengguang Guo , Eli Song , Sucan Ma , Xiaorong Wang , Shijuan Gao , Chen Shao , Siqi Hu , Lulu Jia , Rui Tian , Tao Xu , Youhe Gao	2012-10-05	PQBP1, PKDREJ, LRRC3B, ADRA1D, EXOC8, CTNND2, CTSO, CXADR, ABCA1, GJD4, SDK1, LNX2, PDZRN3, DOCK9, CDC42EP4, GAS2L2, CLDN17, MDGA1, GIPR, ARHGEF16, GRIN1, ABR, PDZRN4, HUNK, HTR2B, GPR142, ILF3, KCNA4, INSC, SHISA2, ARHGAP6, ARVCF, CITED1, NRCAM, BPIFA1, ABCB1, SLC6A15, PBK, PTGIR, CGN, LGR6, BCR, SSTR3, STRN, TSC2, TYRO3, UBE2D2, VRK2, WNT8A, NUP37, LNX1, PKP4, CBX4, TNFRSF18, KALRN, CLDN2, CLDN1, SLC6A5, ORMDL3, JOSD1
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
20944657	Replication of top markers of a genome-wide association study in multiple sclerosis in Spain. Genes Immun. M L Cavanillas , O FernÃ¡ndez , M Comabella , A Alcina , M Fedetz , G Izquierdo , M Lucas , M C CÃ©nit , R Arroyo , K Vandenbroeck , I Alloza , M GarcÃa-Barcina , A AntigÃ¼edad , L Leyva , C L GÃ³mez , J Olascoaga , D Otaegui , Y Blanco , A Saiz , X MontalbÃ¡n , F Matesanz , E Urcelay	2011-03-01	EN1, GPC5, TRIB2, PDZRN4, SLC25A36, TMEM74B, TBC1D2, CSMD1, SH3GL2, ZIC1, ASAP2, LOC90768
19010793	Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Hum. Mol. Genet. Sergio E Baranzini , Joanne Wang , Rachel A Gibson , Nicholas Galwey , Yvonne Naegelin , Frederik Barkhof , Ernst-Wilhelm Radue , Raija L P Lindberg , Bernard M G Uitdehaag , Michael R Johnson , Aspasia Angelakopoulou , Leslie Hall , Jill C Richardson , Rab K Prinjha , Achim Gass , Jeroen J G Geurts , Jolijn Kragt , Madeleine Sombekke , Hugo Vrenken , Pamela Qualley , Robin R Lincoln , Refujia Gomez , Stacy J Caillier , Michaela F George , Hourieh Mousavi , Rosa Guerrero , Darin T Okuda , Bruce A C Cree , Ari J Green , Emmanuelle Waubant , Douglas S Goodin , Daniel Pelletier , Paul M Matthews , Stephen L Hauser , Ludwig Kappos , Chris H Polman , Jorge R Oksenberg	2009-02-15	LOC101927998, CHRND, AXDND1, CBLN2, EN1, NLRP11, GPC5, FOXO3, WDR7, RAB38, CPAMD8, TRIM42, PDZRN4, KCNIP1, NCKAP5, IGF2R, JARID2, C16orf47, LEKR1, MET, MXI1, PCSK5, ACP5, SLC25A36, RFK, RELN, C1GALT1, BICD1, RAD21L1, SGCD, CSMD1, SH3GL2, SVIL, UGT1A, ZIC1, NUBPL, BUD13, ASAP2, LOC90768, KCNB2
18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs). PLoS Genet. David Melzer , John R B Perry , Dena Hernandez , Anna-Maria Corsi , Kara Stevens , Ian Rafferty , Fulvio Lauretani , Anna Murray , J Raphael Gibbs , Giuseppe Paolisso , Sajjad Rafiq , Javier Simon-Sanchez , Hana Lango , Sonja Scholz , Michael N Weedon , Sampath Arepalli , Neil Rice , Nicole Washecka , Alison Hurst , Angela Britton , William Henley , Joyce van de Leemput , Rongling Li , Anne B Newman , Greg Tranah , Tamara Harris , Vijay Panicker , Colin Dayan , Amanda Bennett , Mark I McCarthy , Aimo Ruokonen , Marjo-Riitta Jarvelin , Jack Guralnik , Stefania Bandinelli , Timothy M Frayling , Andrew Singleton , Luigi Ferrucci	2008-05-01	LINC00624, TARID, KIRREL3-AS2, GADD45G, OSBPL1A, CNTN1, COL11A1, CRP, CDAN1, CTNNA2, DLG2, DOCK2, DSC3, DUT, KHDRBS2, EPS8, EYA4, FGF3, SASH1, EPC2, SACS, GGT1, GJA1, ABO, SH2D6, PDZRN4, NXPH1, HLA-C, IL1RN, IL6R, IL18, KCNQ1, CCL4L1, LPA, MIR2052HG, ATP2A2, PAFAH1B2, PI15, WDPCP, FAM49B, BCO1, POLR2A, GDAP1, DIRAS2, TMEM38B, STARD9, ROBO1, ROBO2, SHBG, CACNB2, C17orf62, DYSF, FZD8, ANGPTL6, BCO2, KIRREL3, IL1F10, ANKRD30A, CHD1L, CCL4L2, HS3ST3B1

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