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29950 SERTAD1

29950

SERTAD1

SERTA domain containing 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition SERTA domain containing 1

研究结论

Date Results Publications
2020-11-21 13:17:00 Inhibitory Role of TRIP-Br1/XIAP in Necroptosis under Nutrient/Serum Starvation. 32050753
2019-04-27 11:53:00 In human PCa tumor tissues, Sertad1 expression is positively correlated with AR expression and the Gleason score. Taken together, this report is the first to show that Sertad1 is a novel AR-LBD-binding protein, and DHT-liganded AR-LBD inhibits Sertad1 degradation. 30230528
2018-07-07 10:43:00 Sertad1 could antagonize iASPP function by hindering its entrance into nuclei to interact with P53 in leukemic cells when iASPP was in the stage of overproduction. 29179704
2018-03-17 10:48:00 Here, the authors show that transcriptional regulator interacting with the PHD-bromodomain 1 (TRIP-Br1, Sertad1), a newly identified protein with poorly characterized functions, acts as an adaptor that bridges the interaction of multiple Adenylyl cyclase isoforms with X-linked inhibitor of apoptosis protein (XIAP), a RING-domain E3 ubiquitin ligase. 28656888
2017-08-19 12:26:00 NEDD4-1 recognizes SERTA domain containing proline rich region of p34SEI-1. Residues of NEDD4-1 responsible for direct interaction with p34SEI-1 are identified by NMR titration experiments. 28666866

名称对应

Type IDs
Synonymous SEI1, TRIP-Br1, TRIPBR1
Gene
UniProtKB-ID: SRTD1_HUMAN, Q53GC0_HUMAN
UniprotKB: Q9UHV2, Q53GC0
UniParc: UPI000006F397
EMBL: BC002670, AK074652, AY130860, AF117959, AF366402, AK223011, AK222970, CH471126
Ensembl: ENSG00000197019
KO: hsa:29950
Nucleutide sequences
EMBL-CDS: AAF08349.1, AAM77800.1, AAH02670.1, AAK52831.1, BAD96690.1, EAW56965.1, BAG51982.1, BAD96731.1, EAW56964.1
Gene_ORFName: hCG_1777718
Ensembl_TRS: ENST00000357949
Protein sequencees
Ensembl_PRO: ENSP00000350633
RefSeq: NP_037508.2
Others
UniRef100: UniRef100_Q9UHV2
UniRef90: UniRef90_Q9UHV2
UniRef50: UniRef50_Q9UHV2
UniGene: Hs.269898
CCDS: CCDS12557.1

全选

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