| Type | Description |
|---|---|
| Definition | protein kinase N3 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:26:00 | A Screen for PKN3 Substrates Reveals an Activating Phosphorylation of ARHGAP18. | 33092266 |
| 2019-12-21 10:55:00 | a novel interaction of p130Cas with Ser/Thr kinase PKN3, is reported. | 30422386 |
| 2018-01-13 12:02:00 | Steady-state kinetic analysis revealed that PKN1-3 follows a sequential ordered Bi-Bi kinetic mechanism, where peptide substrate binding is preceded by ATP binding. This kinetic mechanism was confirmed by additional kinetic studies for product inhibition and affinity of small molecule inhibitors. | 27919031 |
| 2016-12-17 11:48:00 | PKN3 is the major regulator of angiogenesis in humans and mice and tumor metastasis in mice. | 26742562 |
| 2013-06-15 11:39:00 | PKN3 can be considered a novel protein implicated in remodeling the actin-adherens junction, possibly by linking ICAM-1-signaling with actin/AJ dynamics. | 22609186 |
| Type | IDs |
|---|---|
| Synonymous | UTDP4-1 |
| Gene |
UniProtKB-ID:
PKN3_HUMAN,
A0A024R8D6_HUMAN
UniprotKB:
Q6P5Z2,
A0A024R8D6
UniParc:
UPI000013E087
EMBL:
AL441992,
BC062558,
AB019692,
CH471090
Ensembl:
ENSG00000160447
KO:
hsa:29941
|
| Nucleutide sequences |
EMBL-CDS:
BAA85625.1,
AAH62558.1,
EAW87824.1,
EAW87825.1
Gene_ORFName:
hCG_96122
Ensembl_TRS:
ENST00000291906
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000291906
RefSeq:
XP_016870139.1,
XP_005252003.1,
XP_006717143.1,
NP_037487.2,
NP_001304855.1,
XP_016870138.1
|
| Others |
UniRef100:
UniRef100_Q6P5Z2
UniRef90:
UniRef90_Q6P5Z2
UniRef50:
UniRef50_Q6P5Z2
UniGene:
Hs.300485
CCDS:
CCDS6908.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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