| Type | Description |
|---|---|
| Definition | heat shock protein 90 alpha family class A member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-25 12:59:00 | Hsp90 is involved in cAMP-induced diffentiation of primary Schwann cells in rats. It stabilizes ErbB2 and promotes nuclear translocation of Gab1 and ERK. | 31606837 |
| 2020-01-11 12:29:00 | Hsp90 is involved in the activation of the Raf/Mek/Erk pathway via stabilization of c-Raf in cardiomyocytes. | 30582930 |
| 2018-03-31 11:50:00 | This study results showed that antipsychotics, particularly those recently synthesized, exerted similar GABAergic interneuron genesis effects on NG2(+) neuronal/glial progenitor cells in the adult rat brain by increasing cellular HSP90 production. | 28414930 |
| 2018-01-20 11:08:00 | Blocking the function of HSP90 with the HSP90 inhibitor geldanamycin or siRNA targeting HSP90 prevented the protection of HPC and the HPC-induced association of Cx43, indicating that mitochondrial HSP90 was important for mitochondrial translocation of Cx43 during HPC. | 29179175 |
| 2017-07-01 10:11:00 | myocyte-derived exosomes and myocyte-secreted IL-6 are responsible in unison for the biphasic activation of signaling in cardiac fibroblasts that culminates in excess collagen synthesis, leading to severely compromised cardiac function during cardiac hypertrophy. | 28031326 |
| Type | IDs |
|---|---|
| Synonymous | Hsp86, Hsp90, Hspca |
| Gene |
UniProtKB-ID:
HS90A_RAT
UniprotKB:
P82995
UniParc:
UPI00000E5F58
EMBL:
BC085120,
BC072489,
AJ297736,
AJ428213
Ensembl:
ENSRNOG00000007219,
ENSRNOG00000059714
KO:
rno:299331,
rno:103692716
|
| Nucleutide sequences |
EMBL-CDS:
AAH72489.1,
CAC39453.1,
AAH85120.1,
CAD21648.1
Ensembl_TRS:
ENSRNOT00000009556,
ENSRNOT00000086310
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000075715,
ENSRNOP00000009556
RefSeq:
NP_786937.1
|
| Others |
UniRef100:
UniRef100_P82995
UniRef90:
UniRef90_P07901
UniRef50:
UniRef50_P07900
UniGene:
Rn.3277,
Rn.119867,
Rn.232226
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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