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29933 GPR132

29933

GPR132

G protein-coupled receptor 132

protein-coding

Homo sapiens

基因描述

Type Description
Definition G protein-coupled receptor 132

研究结论

Date Results Publications
2021-01-23 13:02:00 Expression profiles of proton-sensing G-protein coupled receptors in common skin tumors. 32948783
2018-04-21 11:29:00 G protein-coupled receptor 132 (Gpr132) functions as a key macrophage sensor of the rising lactate in the acidic tumor milieu to mediate the reciprocal interaction between cancer cells and macrophages during breast cancer metastasis. Lactate activates macrophage Gpr132 to promote the alternatively activated macrophage (M2)-like phenotype, which, in turn, facilitates cancer cell adhesion, migration, and invasion. 28049847
2018-03-17 10:40:00 High GPR132 expression is associated with acute lymphoblastic leukemia. 27588474
2017-04-08 10:58:00 coexpression of OGR1- and G2A-enhanced proton sensitivity and proton-induced calcium signals. This alteration is attributed to oligomerization of OGR1 and G2A. The oligomeric potential locates receptors at a specific site, which leads to enhanced 27049592
2010-04-07 21:40:00 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and genetic testing. (HuGE Navigator) 19948975

名称对应

Type IDs
Synonymous G2A
Gene
UniProtKB-ID: GP132_HUMAN
UniprotKB: Q9UNW8
UniParc: UPI00001B2494, UPI0000050461, UPI0000071E1D
EMBL: EU432121, CH471061, AK303654, AL512356, BT007257, AK292142, AF083955, BC004555, AB465600, AB465599, BC084546
Ensembl: ENSG00000183484
KO: hsa:29933
Nucleutide sequences
EMBL-CDS: AAD47380.1, ABY87920.1, BAG64656.1, AAP35921.1, AAH84546.1, BAG84610.1, BAG84609.1, BAF84831.1, EAW81898.1
Ensembl_TRS: ENST00000392585, ENST00000329797, ENST00000539291
Protein sequencees
Ensembl_PRO: ENSP00000328818, ENSP00000376364, ENSP00000438094
RefSeq: NP_001265623.1, NP_001265624.1, NP_037477.1, NP_001265625.1
Others
UniRef100: UniRef100_Q9UNW8
UniRef90: UniRef90_Q9UNW8
UniRef50: UniRef50_Q9UNW8
UniGene: Hs.532504
CCDS: CCDS9997.1, CCDS61567.1

全选

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