| Type | Description |
|---|---|
| Definition | hypoxia inducible lipid droplet associated |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:06:00 | Hypoxia, hypoxia-inducible gene 2 (HIG2)/HILPDA, and intracellular lipolysis in cancer. | 32818550 |
| 2020-07-18 12:43:00 | Lipidomic analysis revealed not only quantitative but also qualitative differences in the glycerolipid and phospholipid profile of HILPDA wild-type and knockout cells, indicating additional HILPDA functions affecting lipid metabolism. | 31308147 |
| 2019-11-30 12:37:00 | HIG2 activates the signaling pathway in NK cells by promoting IL-10 release by HCC cells, thereby inhibiting the killing activity of NK cells, and subsequently promoting the recurrence and metastasis of HCC. | 31142329 |
| 2019-07-27 10:53:00 | Expression changes in secreted frizzled-related protein 2, stearoyl-CoA desaturase, and hypoxia inducible lipid droplet-associated (HILPDA) with weight loss were confirmed by reverse transcription quantitative polymerase chain reaction. Dietary weight loss induces significant changes in the expression of genes implicated in lipid metabolism (SCD and HILPDA) and WNT-signaling (SFRP2) in subcutaneous adipose tissue. | 30884788 |
| 2019-07-27 10:27:00 | hypoxia-inducible lipid droplet-associated protein inhibits adipose triglyceride lipase | 29326160 |
| Type | IDs |
|---|---|
| Synonymous | C7orf68, HIG-2, HIG2 |
| Gene |
UniProtKB-ID:
HLPDA_HUMAN
UniprotKB:
Q9Y5L2
UniParc:
UPI00000396B9
EMBL:
BC001863,
AK222583,
BC093742,
AF144755,
BC112183,
CH236947
Ensembl:
ENSG00000135245
KO:
hsa:29923
|
| Nucleutide sequences |
EMBL-CDS:
AAD37585.1,
EAL24309.1,
AAH01863.1,
AAH93742.1,
AAI12184.1,
BAD96303.1
Ensembl_TRS:
ENST00000435296,
ENST00000257696
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000257696,
ENSP00000388871
RefSeq:
NP_001092256.1,
NP_037464.1
|
| Others |
UniRef100:
UniRef100_Q9Y5L2
UniRef90:
UniRef90_Q9Y5L2
UniRef50:
UniRef50_Q9Y5L2
UniGene:
Hs.706124
CCDS:
CCDS5802.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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