Molecular Basis for PI(3,5)P₂ Recognition by SNX11, a Protein Involved in Lysosomal Degradation and Endosome Homeostasis Regulation.

J Mol Biol     Tingting Xu , Qingqing Gan , Bin Wu , Menghui Yin , Jinxin Xu , Xiaodong Shu , Jinsong Liu

A reference map of the human binary protein interactome.

Nature     Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat Taşan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood

SNX11 Identified as an Essential Host Factor for SFTS Virus Infection by CRISPR Knockout Screening.

Virol Sin     Tiezhu Liu , Jiajia Li , Yang Liu , Yuanyuan Qu , Aqian Li , Chuan Li , Quanfu Zhang , Wei Wu , Jiandong Li , Yan Liu , Dexin Li , Shiwen Wang , Mifang Liang

Architecture of the human interactome defines protein communities and disease networks.

Nature     Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper

The BioPlex Network: A Systematic Exploration of the Human Interactome.

Cell     Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi

A proteome-scale map of the human interactome network.

Cell     Thomas Rolland , Murat Taşan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal

Structure of sorting nexin 11 (SNX11) reveals a novel extended phox homology (PX) domain critical for inhibition of SNX10-induced vacuolation.

J Biol Chem     Jinxin Xu , Tingting Xu , Bin Wu , Yinghua Ye , Xiaojuan You , Xiaodong Shu , Duanqing Pei , Jinsong Liu

Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32.

Hum. Mol. Genet.     EPICURE Consortium , EMINet Consortium , Michael Steffens , Costin Leu , Ann-Kathrin Ruppert , Federico Zara , Pasquale Striano , Angela Robbiano , Giuseppe Capovilla , Paolo Tinuper , Antonio Gambardella , Amedeo Bianchi , Angela La Neve , Giovanni Crichiutti , Carolien G F de Kovel , Dorothée Kasteleijn-Nolst Trenité , Gerrit-Jan de Haan , Dick Lindhout , Verena Gaus , Bettina Schmitz , Dieter Janz , Yvonne G Weber , Felicitas Becker , Holger Lerche , Bernhard J Steinhoff , Ailing A Kleefuß-Lie , Wolfram S Kunz , Rainer Surges , Christian E Elger , Hiltrud Muhle , Sarah von Spiczak , Philipp Ostertag , Ingo Helbig , Ulrich Stephani , Rikke S Møller , Helle Hjalgrim , Leanne M Dibbens , Susannah Bellows , Karen Oliver , Saul Mullen , Ingrid E Scheffer , Samuel F Berkovic , Kate V Everett , Mark R Gardiner , Carla Marini , Renzo Guerrini , Anna-Elina Lehesjoki , Auli Siren , Michel Guipponi , Alain Malafosse , Pierre Thomas , Rima Nabbout , Stephanie Baulac , Eric Leguern , Rosa Guerrero , Jose M Serratosa , Philipp S Reif , Felix Rosenow , Martina Mörzinger , Martha Feucht , Fritz Zimprich , Claudia Kapser , Christoph J Schankin , Arvid Suls , Katrin Smets , Peter De Jonghe , Albena Jordanova , Hande Caglayan , Zuhal Yapici , Destina A Yalcin , Betul Baykan , Nerses Bebek , Ugur Ozbek , Christian Gieger , Heinz-Erich Wichmann , Tobias Balschun , David Ellinghaus , Andre Franke , Christian Meesters , Tim Becker , Thomas F Wienker , Anne Hempelmann , Herbert Schulz , Franz Rüschendorf , Markus Leber , Steffen M Pauck , Holger Trucks , Mohammad R Toliat , Peter Nürnberg , Giuliano Avanzini , Bobby P C Koeleman , Thomas Sander

A germline-specific class of small RNAs binds mammalian Piwi proteins.

Nature     Angélique Girard , Ravi Sachidanandam , Gregory J Hannon , Michelle A Carmell

Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.

Genome Res.     Kouichi Kimura , Ai Wakamatsu , Yutaka Suzuki , Toshio Ota , Tetsuo Nishikawa , Riu Yamashita , Jun-ichi Yamamoto , Mitsuo Sekine , Katsuki Tsuritani , Hiroyuki Wakaguri , Shizuko Ishii , Tomoyasu Sugiyama , Kaoru Saito , Yuko Isono , Ryotaro Irie , Norihiro Kushida , Takahiro Yoneyama , Rie Otsuka , Katsuhiro Kanda , Takahide Yokoi , Hiroshi Kondo , Masako Wagatsuma , Katsuji Murakawa , Shinichi Ishida , Tadashi Ishibashi , Asako Takahashi-Fujii , Tomoo Tanase , Keiichi Nagai , Hisashi Kikuchi , Kenta Nakai , Takao Isogai , Sumio Sugano