| Type | Description |
|---|---|
| Definition | eukaryotic elongation factor 2 kinase |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:21:00 | eEF2K enhances expression of PD-L1 by promoting the translation of its mRNA. | 33094805 |
| 2020-06-20 11:14:00 | This study determined the solution structure of a C-terminal fragment of eEF-2K, eEF-2K562-725 that encodes two alpha-helical repeats. | 31108082 |
| 2020-04-11 10:55:00 | Regulation of eEF2K mRNA abundance by TNFalpha Is dependent upon canonical NF-kappaB signaling and the p65 NF-kappaB subunit. | 31636182 |
| 2020-02-08 12:52:00 | Knocking down eEF2K also led to a striking decrease in the phosphorylation of PI3K/Akt and indicating inactivation of these tumorigenic pathways. Data suggest that eEF2K contributes to angiogenesis and tumor progression in HCC via SP1/KLF5-mediated VEGF expression, as well as the subsequent stimulation of PI3K/Akt and signaling. | 31286509 |
| 2020-02-08 11:42:00 | Eukaryotic elongation factor-2 kinase mediates cross-talk between DFNA5-mediated pyroptosis and autophagy in doxorubicin-treated human melanoma cells. | 30914761 |
| Type | IDs |
|---|---|
| Synonymous | CaMKIII, HSU93850, eEF-2K |
| Gene |
UniProtKB-ID:
EF2K_HUMAN
UniprotKB:
O00418
UniParc:
UPI000013D387
EMBL:
AC009034,
U93850,
BC032665
Ensembl:
ENSG00000103319
KO:
hsa:29904
|
| Nucleutide sequences |
EMBL-CDS:
AAH32665.1,
AAB58270.1
Ensembl_TRS:
ENST00000263026
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000263026
RefSeq:
NP_037434.2,
XP_016878682.1,
XP_016878683.1
|
| Others |
UniRef100:
UniRef100_O00418
UniRef90:
UniRef90_O00418
UniRef50:
UniRef50_O00418
UniGene:
Hs.498892
CCDS:
CCDS10604.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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