| Type | Description |
|---|---|
| Definition | coiled-coil domain containing 106 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-27 12:18:00 | Study revealed a CK2/CCDC106/p53 signaling axis in the progression of breast and cervical cancers. | 30885251 |
| 2018-03-10 10:36:00 | Our studies revealed that CCDC106 is associated with non-small cell lung cancer progression and unfavorable prognosis. CCDC106 enhanced Cyclin A2 and Cyclin B1 expression and promoted A549 and H1299 cell proliferation, which depended on AKT signaling. These results suggest that CCDC106 may be a novel target for lung cancer treatment. | 28460455 |
| 2010-05-03 12:09:00 | CCDC106 promotes the degradation of p53 protein and inhibits its transactivity. | 20159018 |
| Type | IDs |
|---|---|
| Synonymous | HSU79303, ZNF581 |
| Gene |
UniProtKB-ID:
CC106_HUMAN
UniprotKB:
Q9BWC9
UniParc:
UPI0000072074
EMBL:
GU354323,
BC008956,
BC000412,
AK097095,
CR450308,
GU354321,
GU354322,
U79303
Ensembl:
ENSG00000173581
KO:
hsa:29903
|
| Nucleutide sequences |
EMBL-CDS:
ADC34062.1,
ADC34061.1,
BAG53421.1,
AAB50227.1,
AAH00412.1,
ADC34060.1,
AAH08956.1,
CAG29304.1
Ensembl_TRS:
ENST00000591578,
ENST00000308964,
ENST00000588740,
ENST00000586790
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000468539,
ENSP00000466870,
ENSP00000309681,
ENSP00000465757
RefSeq:
NP_001357397.1,
NP_037433.2,
NP_001357398.1,
NP_001357399.1,
NP_001357400.1,
NP_001357396.1
|
| Others |
UniRef100:
UniRef100_Q9BWC9
UniRef90:
UniRef90_Q9BWC9
UniRef50:
UniRef50_Q9BWC9
UniGene:
Hs.82482
CCDS:
CCDS33118.1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
Institute for Research in Biomedicine (IRB Barcelona) |
3 |
| 2 |
Dana-Farber Cancer Institute |
3 |
| 3 |
McGill University |
2 |
| 4 |
University of Toronto |
2 |
| 5 |
Wright State University |
2 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
Fana Gebreab |
4 |
| 2 |
Stanley Tam |
4 |
| 3 |
Andrew MacWilliams |
3 |
| 4 |
David E Hill |
3 |
| 5 |
Yu Xia |
3 |