| Type | Description |
|---|---|
| Definition | transformer 2 alpha homolog |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 10:30:00 | we knocked down three regulators respectively and found two of them (TRA2A and CAPRIN1) selectively promoted the methylations of the m6A sites co-localized with their binding targets on RNAs through physical interactions with the m6A writers. Knockdown of TRA2A increased the stabilities of the RNAs with TRA2A bound near the m6A sites and decreased the viability of cells | 31912146 |
| 2019-10-05 11:48:00 | Overexpression of TRA2A in glioma SHG44 cell lines promoted the tumor cells proliferation, migration, invasion and epithelial mesenchymal transition (EMT), while, knockdown of TRA2A showed the opposite effect. | 30367895 |
| 2018-03-31 12:06:00 | our findings suggest that paclitaxel targets the TRA2A-RSRC2 splicing pathway, and deregulated TRA2A and RSRC2 expression may confer paclitaxel resistance. In addition, our study demonstrates that expression of TRA2A in conjunction with RSRC2 may provide valuable molecular biomarker evidence for triple-negative breast cancer (TNBC)clinical treatment decisions and patient outcome | 28416606 |
| 2016-02-06 11:04:00 | Overexpression of either Tra2alpha or Tra2beta results in a marked reduction in HIV-1 Gag/ Env expression. | 25970345 |
| 2013-04-27 11:13:00 | findings show the inclusion of both HIV-1 exon 3 and vpr mRNA processing is promoted by an exonic splicing enhancer (ESEvpr) localized between exonic splicing silencer ESSV and 5'ss D3; the ESEvpr sequence was found to be bound by members of the Tra2 protein family | 23255807 |
| Type | IDs |
|---|---|
| Synonymous | AWMS1, HSU53209 |
| Gene |
UniProtKB-ID:
TRA2A_HUMAN,
Q549U1_HUMAN
UniprotKB:
Q13595,
Q549U1
UniParc:
UPI000002B5D3,
UPI00006E0AB9,
UPI00017A772D,
UPI00001372AB
EMBL:
AB097048,
AK314801,
AC023105,
AK298815,
U53209,
AK300741,
BC017094,
AK300565,
CH471073
Ensembl:
ENSG00000164548
KO:
hsa:29896
|
| Nucleutide sequences |
EMBL-CDS:
BAG62271.1,
BAG60948.1,
AAH17094.1,
AAC50658.1,
BAG62410.1,
BAC77401.1,
AAQ96870.1,
EAW93788.1,
BAG37329.1
Gene_ORFName:
hCG_37979
Ensembl_TRS:
ENST00000297071,
ENST00000621813,
ENST00000538367,
ENST00000392502
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000297071,
ENSP00000441116,
ENSP00000376290,
ENSP00000480822
RefSeq:
XP_016867579.1,
NP_037425.1,
NP_001349688.1,
NP_001269687.1,
NP_001349689.1,
NP_001269688.1,
NP_001349690.1,
NP_001269686.1
|
| Others |
UniRef100:
UniRef100_Q13595
UniRef90:
UniRef90_Q13595
UniRef50:
UniRef50_Q13595
UniGene:
Hs.445652
CCDS:
CCDS75569.1,
CCDS5383.1,
CCDS64609.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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