| Type | Description |
|---|---|
| Definition | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma |
| Date | Results | Publications |
|---|---|---|
| 2018-09-15 11:53:00 | The PI3K/mTOR/AKT pathway is known to regulate cell growth, survival, and proliferation and has more recently been shown to be a central mediator of HCC cell survival to heat stress. | 29737948 |
| 2018-02-24 11:06:00 | Suggest that when cardiomyocytes incur oxidative stress under diabetic conditions, it subsequently activates the PI3Kgamma/Akt cell-signaling pathway and further increases HMGB1 expression. | 27821807 |
| 2018-02-24 10:26:00 | Taken together, our results demonstrate that HPC appears to confer neuroprotection against retinal IRI via the PI3K/Akt pathway. | 29288664 |
| 2017-12-16 12:03:00 | These findings suggested that exercise dampened the secretion of inflammation mediators probably through partial inhibition of TLR4 and p-NF-kappaB and activation of PI3K/p-Akt expression in the spleen. | 27539497 |
| 2017-09-16 13:06:00 | Exendin-4 ameliorates HG-induced cardiomyocyte apoptosis, and the mechanisms may involve anti-oxidative stress via the HO-1/Nrf-2 system, as well as intervention of the PI3K/AKT signaling pathway. | 28464602 |
| Type | IDs |
|---|---|
| Synonymous | Pi3k |
| Gene |
UniProtKB-ID:
D3ZFJ0_RAT
UniprotKB:
D3ZFJ0
UniParc:
UPI0000250635
EMBL:
AABR07063826
Ensembl:
ENSRNOG00000009385
KO:
rno:298947
|
| Nucleutide sequences |
Ensembl_TRS:
ENSRNOT00000012487
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000012487
RefSeq:
XP_006240066.1,
XP_003750188.1,
NP_001358229.1,
XP_017458652.1,
XP_006240067.1,
XP_006240065.1
|
| Others |
UniRef100:
UniRef100_D3ZFJ0
UniRef90:
UniRef90_P48736
UniRef50:
UniRef50_P48736
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.proteinEnsembl}} |
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||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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||||
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