| Type | Description |
|---|---|
| Definition | CCR4-NOT transcription complex subunit 7 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:30:00 | CNOT7 modulates biological functions of ovarian cancer cells via AKT signaling pathway. | 33412213 |
| 2019-12-14 11:57:00 | Data show that incorporation of ATP-dependent RNA helicase eIF4A-2 (eIF4A2) into the CCR4-NOT complex inhibits CCR4-NOT transcription complex subunit 7 (CNOT7) deadenylation activity. | 31180491 |
| 2019-11-16 12:15:00 | Active 1-hydroxy-xanthines inhibit both isolated Caf1 (CNOT7) enzyme and human Caf1-containing complexes that also contain the second nuclease subunit Ccr4 (CNOT6L) to a similar extent, indicating that the active site of the Caf1 nuclease subunit does not undergo substantial conformational change when bound to other Ccr4-Not subunits. | 30984545 |
| 2017-10-28 11:09:00 | Findings suggest a preferential involvement of CNOT7 variant 2 (CNOT7v2) in nuclear processes, such as arginine methylation and alternative splicing, rather than mRNA turnover | 28591869 |
| 2016-05-28 10:29:00 | MEX3C associates with the cytoplasmic deadenylation complexes and ubiquitinates CNOT7. | 26471122 |
| Type | IDs |
|---|---|
| Synonymous | CAF-1, CAF1, Caf1a, hCAF-1 |
| Gene |
UniProtKB-ID:
CNOT7_HUMAN,
Q96IQ6_HUMAN
UniprotKB:
Q9UIV1,
Q96IQ6
UniParc:
UPI000013C4DB,
UPI000007000C,
UPI00001F6D70
EMBL:
AK023466,
BC070187,
AF086915,
AC091050,
CH471080,
BC007315,
AK021808,
L46722,
BT006685,
BC060852
Ensembl:
ENSG00000198791
KO:
hsa:29883
|
| Nucleutide sequences |
EMBL-CDS:
AAF01500.1,
EAW63821.1,
EAW63822.1,
AAP97145.1,
BAG51197.1,
EAW63823.1,
EAW63820.1,
AAH70187.1,
BAG51053.1,
AAH60852.1,
AAH07315.1,
AAP35331.1
Ensembl_TRS:
ENST00000361272,
ENST00000523917
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000429093,
ENSP00000355279
RefSeq:
NP_001309021.1,
NP_001309016.1,
NP_001309020.1,
NP_001309017.1,
NP_001309024.1,
NP_001309023.1,
NP_001309026.1,
NP_001309025.1,
NP_001309027.1,
NP_001309028.1,
NP_001309029.1,
XP_005273538.1,
NP_001309022.1,
NP_473367.2,
NP_001309019.1,
NP_037486.2,
NP_001309018.1
|
| Others |
UniRef100:
UniRef100_Q96IQ6,
UniRef100_Q9UIV1
UniRef90:
UniRef90_H2RHZ2,
UniRef90_Q9UIV1
UniRef50:
UniRef50_A0A4X1U0F0,
UniRef50_Q9UIV1
UniGene:
Hs.645009,
Hs.729775
CCDS:
CCDS55202.1,
CCDS6000.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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