| Type | Description |
|---|---|
| Definition | NPC1 like intracellular cholesterol transporter 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:14:00 | A new system to evaluate characteristics of Niemann-Pick C1 Like 1-mediated cholesterol transport using Xenopus laevis oocytes. | 33188743 |
| 2021-03-20 13:27:00 | Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins. | 32410728 |
| 2020-09-26 13:04:00 | Selective Ah receptor modulators attenuate NPC1L1-mediated cholesterol uptake through repression of SREBP-2 transcriptional activity. | 31417158 |
| 2020-08-22 15:24:00 | Nonglucuronidated Ezetimibe Disrupts CD13- and CD64-Coassembly in Membrane Microdomains and Decreases Cellular Cholesterol Content in Human Monocytes/Macrophages. | 30994973 |
| 2020-06-06 13:33:00 | Hepatic NPC1L1 exacerbates diet-induced steatosis, which was accompanied by decreased hepatic ability of VLDL-TG secretion. The obtained results provide a deeper understanding of L1-Tg mice as a promising NAFLD animal model that is able to re-absorb biliary-secreted cholesterol similar to humans | 31883528 |
| Type | IDs |
|---|---|
| Synonymous | LDLCQ7, NPC11L1, SLC65A2 |
| Gene |
UniProtKB-ID:
NPCL1_HUMAN,
A0A0C4DFX6_HUMAN
UniprotKB:
Q9UHC9,
A0A0C4DFX6
UniParc:
UPI000013DF88,
UPI000443803B,
UPI000292A26F,
UPI000015C225,
UPI000006DF38
EMBL:
AY515256,
FJ481111,
CH236960,
AC004938,
AF192523,
AY437865,
CH471128,
AF192522,
BC117178,
BC143756
Ensembl:
ENSG00000015520
KO:
hsa:29881
|
| Nucleutide sequences |
EMBL-CDS:
AAF20397.1,
EAW61096.1,
AAS56939.1,
AAI43757.1,
AAF20396.1,
EAW61097.1,
AAR97886.1,
AAI17179.1,
EAL23753.1,
ACL18055.1,
EAW61098.1
Ensembl_TRS:
ENST00000423141,
ENST00000289547,
ENST00000381160
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000404670,
ENSP00000289547,
ENSP00000370552
RefSeq:
NP_001287896.1,
NP_037521.2,
NP_001095118.1,
XP_011513630.1,
XP_011513628.1
|
| Others |
UniRef100:
UniRef100_Q9UHC9,
UniRef100_A0A0C4DFX6
UniRef90:
UniRef90_Q9UHC9,
UniRef90_Q9UHC9-2
UniRef50:
UniRef50_Q9UHC9
UniGene:
Hs.567486
CCDS:
CCDS5491.1,
CCDS75587.1,
CCDS43575.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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