Type | Description |
---|---|
Definition | chloride intracellular channel 4 (mitochondrial) |
Date | Results | Publications |
---|---|---|
2018-07-07 11:56:00 | Results demonstrate that down-regulating CLIC4 inhibit the proliferation and promotes the apoptosis of mouse liver cancer Hca-F cell. | 28636115 |
2017-12-09 11:44:00 | Results indicate CLICs (CLIC1, CLIC4 and CLIC5)-dependent chloride efflux as an essential and proximal upstream event for NLRP3 activation. | 28779175 |
2017-08-12 10:16:00 | Data, including data from studies in primary cells from knockout mice, suggest Clic1 and Clic4 participate in signaling interleukin 1beta secretion and in activation of Nlrp3 inflammasomes; in LPS macrophage activation, Clic1 and Clic4 are translocated to nucleus/cell membranes. (Clic1 = chloride intracellular channel 1; Clic4 = chloride intracellular channel 4, mitochondrial; Nlrp3 = NLR family pyrin domain containing 3) | 28576828 |
2017-07-29 11:27:00 | study reports an alternately-spliced form of Smad7, Smad7Delta, that is induced by TGF-beta and CLIC4, is a dominant inhibitor of Smad7 and enhances TGF-beta signaling | 27536941 |
2017-07-08 10:11:00 | The findings indicate that CLIC4/CLIC5A-mediated ERM activation is required for maintenance of the glomerular capillary architecture. | 27582103 |
Type | IDs |
---|---|
Synonymous | D0Jmb3, TU-74, mc3s5, mtCLIC |
Gene |
UniProtKB-ID:
CLIC4_MOUSE,
Q543N5_MOUSE
UniprotKB:
Q9QYB1,
Q543N5
UniParc:
UPI0000004099
EMBL:
AK172516,
AK159402,
AK152273,
AK172026,
AK153432,
AK169376,
AK171243,
AK170942,
AF102578,
AK150993,
BC052890,
AK169834,
AK160856,
AK166794,
AK031211,
AK155826,
AK049191,
BC046384,
AK172660,
CT010279
Ensembl:
ENSMUSG00000037242
KO:
mmu:29876
|
Nucleutide sequences |
EMBL-CDS:
AAF19055.1,
BAC27301.1,
AAH52890.1,
AAH46384.1,
BAE31089.1,
BAE39023.1,
BAE33450.1,
BAC33601.1,
BAE42784.1,
BAE43120.1,
BAE35054.1,
BAE41124.1,
BAE42336.1,
BAE30017.1,
BAE42130.1,
CAJ18487.1,
BAE41399.1,
BAE36049.1,
BAE31990.1,
BAE43045.1
Ensembl_TRS:
ENSMUST00000037099
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000041453
RefSeq:
NP_038913.1
|
Others |
UniRef100:
UniRef100_Q9QYB1
UniRef90:
UniRef90_Q9QYB1
UniRef50:
UniRef50_Q9QYB1
UniGene:
Mm.257765
CCDS:
CCDS18783.1
|
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