| Type | Description |
|---|---|
| Definition | TAR DNA binding protein |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 12:58:00 | Astrocytes with TDP-43 inclusions exhibit reduced noradrenergic cAMP and Ca(2+) signaling and dysregulated cell metabolism. | 32265469 |
| 2020-08-01 12:06:00 | Knockdown of TDP-43 in astrocytes results in accumulation of repetitive element transcripts and dsRNA and innate immune activation. | 31229690 |
| 2020-03-28 10:24:00 | These findings suggest that TDP-43 may regulate activity-dependent neuronal plasticity, possibly by regulating the splicing of genes that are responsible for fast synaptic transmission and membrane potential. | 31176717 |
| 2019-10-12 11:58:00 | results indicate that redundant pathways regulate TDP43 nuclear export | 29545601 |
| 2019-05-11 11:53:00 | Temporal expression of mutant TDP-43 in neurons promoted serious phenotype in an animal model of Amyotrophic Lateral Sclerosis. | 29313467 |
| Type | IDs |
|---|---|
| Synonymous | Tdp-43 |
| Gene |
UniProtKB-ID:
I6L9G6_RAT
UniprotKB:
I6L9G6
UniParc:
UPI0000444703
EMBL:
AABR07050449,
BC083752,
CH473968
Ensembl:
ENSRNOG00000012455
KO:
rno:298648
|
| Nucleutide sequences |
EMBL-CDS:
AAH83752.1,
EDL81134.1
Gene_ORFName:
rCG_31562
Ensembl_TRS:
ENSRNOT00000049822
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000041889
RefSeq:
XP_008762456.1,
XP_006239448.1,
XP_006239444.1,
XP_006239446.1,
XP_008762457.1,
XP_006239447.1,
XP_008762458.1,
NP_001011979.1
|
| Others |
UniRef100:
UniRef100_I6L9G6
UniRef90:
UniRef90_I6L9G6
UniRef50:
UniRef50_I6L9G6
UniGene:
Rn.2633
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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