| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase 12 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-21 10:54:00 | In mouse hepatocytes, p38gamma induces proliferation after partial hepatectomy by promoting the phosphorylation of retinoblastoma tumour suppressor protein at known CDK target residues. Lack of p38gamma or treatment with the p38gamma inhibitor pirfenidone protects against the chemically induced formation of liver tumours. | 30971822 |
| 2019-03-30 12:04:00 | Mitogen-activated protein kinases p38gamma/p38delta deficiency protects against Candida albicans infection by increasing reactive oxygen species and iNOS enzyme production and thus the antifungal capacity of neutrophils and macrophages. | 29661910 |
| 2016-07-30 11:24:00 | p38gamma mitogen-activated protein kinase mediates inflammatory signaling to promote colon tumorigenesis | 25961922 |
| 2016-07-30 10:11:00 | p38gamma and p38delta reprogram liver metabolism by modulating neutrophil infiltration and provide a potential target for NAFLD therapy | 26843485 |
| 2016-06-11 11:56:00 | p38gamma and p38delta control heart growth by modulating mTOR pathway through DEPTOR phosphorylation and subsequent degradation. | 26795633 |
| Type | IDs |
|---|---|
| Synonymous | AW123708, Erk6, P38gamma, Prkm12, Sapk3 |
| Gene |
UniProtKB-ID:
MK12_MOUSE
UniprotKB:
O08911
UniParc:
UPI0000027D60
EMBL:
BC021640,
AK011286,
Y13439
Ensembl:
ENSMUSG00000022610
KO:
mmu:29857
|
| Nucleutide sequences |
EMBL-CDS:
CAA73850.1,
AAH21640.1
Ensembl_TRS:
ENSMUST00000088827
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000086207
RefSeq:
XP_036015349.1,
XP_006521121.1,
XP_036015350.1,
NP_038899.1,
XP_006521124.1,
XP_006521123.1,
XP_006521122.1
|
| Others |
UniRef100:
UniRef100_O08911
UniRef90:
UniRef90_Q63538
UniRef50:
UniRef50_Q16539
UniGene:
Mm.38343
CCDS:
CCDS27740.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员