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29841 GRHL1

29841

GRHL1

grainyhead like transcription factor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition grainyhead like transcription factor 1

研究结论

Date Results Publications
2019-07-20 10:18:00 Structural basis of DNA target-site recognition by grainyhead-like 1. 29309642
2018-08-18 11:11:00 Non-melanoma skin cancer growth is accompanied by coordinated reduced expression of epidermal differentiation genes: GRHL1 and GRHL3, which may be regulated by miR-21-3p and -5p, respectively. Some potentially damaging single nucleotide polymorphisms in GRHL genes occur with altered frequencies in NMSC patients, and they may in particular impair the expression of GRHL3 gene or functioning of encoded protein 29301499
2017-11-26 01:40:00 All of these processes involve epithelial-mesencyhmal transition (EMT), MET or a sequence of both, suggesting that the GRHL factors((GRHL1, GRHL2 and GRHL3), could potentially affect tumor initiation and progression via EMT 28714958
2017-02-18 10:49:00 it was observed that ER stimulated gene expression by interacting with MEIS1 and FOXP3, and ER inhibited gene expression by interacting with THRB and GRHL1. 27035558
2016-11-05 12:11:00 Grhl1 deficiency affects inner ear development in zebrafish. 25896282

名称对应

Type IDs
Synonymous LBP32, MGR, NH32, TFCP2L2
Gene
UniProtKB-ID: GRHL1_HUMAN
UniprotKB: Q9NZI5
UniParc: UPI000006ED87, UPI00001E0586, UPI00006C21A5
EMBL: BC067519, AF411210, AF198489, AK312950, AC010969, CH471053, BC067520, BC067521
Ensembl: ENSG00000134317
KO: hsa:29841
Nucleutide sequences
EMBL-CDS: AAH67521.1, AAH67520.1, AAM22616.1, AAF32276.1, BAG35791.1, EAX00973.1, AAX93273.1, AAH67519.1
Ensembl_TRS: ENST00000472167, ENST00000324907, ENST00000405379
Protein sequencees
Ensembl_PRO: ENSP00000384209, ENSP00000324693, ENSP00000418275
RefSeq: XP_006711947.1, XP_006711945.1, XP_016859390.1, NP_937825.2, XP_011508645.1, XP_016859389.1, XP_005246216.1
Others
UniRef100: UniRef100_Q9NZI5
UniRef90: UniRef90_Q9NZI5
UniRef50: UniRef50_Q9NZI5
UniGene: Hs.418493
CCDS: CCDS33144.2

全选

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