| Type | Description |
|---|---|
| Definition | proprotein convertase subtilisin/kexin type 9 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:21:00 | PCSK9 inhibition as a novel therapeutic target for alcoholic liver disease. | 31748600 |
| 2019-04-27 10:55:00 | This suggests that overexpression of HNF1alpha gene in liver of lipectomized rats can lead to overproduction of PCSK9. In conclusion, up-regulation of PCSK9, due to overexpression of HNF1alpha gene in liver of lipectomized rats and subsequently increase in circulating PCSK9 concentration lead to decrease in liver LDL-R level. | 30483910 |
| 2018-10-06 11:56:00 | up-regulation of intestinal gene expression of LDL-R and PCSK9 following voluntary wheel running | 29938676 |
| 2018-06-16 10:17:00 | This is the first report about the expression of PCSK9 in adult terminal differentiated ventricular cardiomyocytes | 28913715 |
| 2017-06-24 11:44:00 | PCSK9 is regulated in vascular smooth muscle cells by TLR-4 - SAPK/JNK signaling, a pathway important in inflammation and metabolism. | 28232185 |
| Type | IDs |
|---|---|
| Synonymous | NARC-1, Narc1, PC9 |
| Gene |
UniProtKB-ID:
PCSK9_RAT
UniprotKB:
P59996
UniParc:
UPI000021CAD0
EMBL:
BC133063,
AX207690,
AY847775
Ensembl:
ENSRNOG00000006280
KO:
rno:298296
|
| Nucleutide sequences |
EMBL-CDS:
AAI33064.1,
CAC60363.1,
AAW31850.1
Ensembl_TRS:
ENSRNOT00000008535
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000008536
RefSeq:
NP_954862.2
|
| Others |
UniRef100:
UniRef100_P59996
UniRef90:
UniRef90_Q80W65
UniRef50:
UniRef50_Q8NBP7
UniGene:
Rn.19195
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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