例如:"NBL1", "4681", "drought"
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29811 Ndrg2

29811

Ndrg2

N-myc downstream regulated gene 2

protein-coding

Mus musculus

基因描述

Type Description
Definition N-myc downstream regulated gene 2

研究结论

Date Results Publications
2020-10-03 12:56:00 N-myc Downstream-Regulated Gene 2 (NDRG2) Promotes Bone Morphogenetic Protein 2 (BMP2)-Induced Osteoblastic Differentiation and Calcification by Janus Kinase 3 (JAK3)/Signal Transducer and Activator of Transcription 3 Signaling Pathway. 31911574
2020-06-06 11:31:00 NDRG2 should be understood as a regulator of synaptic plasticity and thus neuronal communications. 31004356
2020-04-11 10:19:00 NDR2 positively regulated an antiviral innate immune response in a kinase activity-independent manner. NDR2 interacts with RIG-I and promotes TRIM25-mediated RIG-I ubiquitination, which is required for downstream signaling activation and type I IFN production. 30775439
2020-03-14 10:25:00 These findings highlight modulatory and co-regulatory roles for miR-23a, -23b and -28 and their novel regulation of NDRG2 during stress conditions in muscle. 31138100
2019-10-26 11:29:00 Study identified FLNa as a substrate of Ndr2 in vitro and demonstrated that Ndr2 phosphorylates FLNa at serine 2152 (S2152) upon TCR-triggering in vivo. Ndr2-dependent phosphorylation of FLNa at S2152 releases the binding of this molecule from the inactive conformation of LFA-1, thus allowing the TCR-mediated association of Talin and Kindlin-3 to the cytoplasmatic domain of CD18. 30568657

名称对应

Type IDs
Synonymous AI182517, AU040374, Ndr2, SYLD
Gene
UniProtKB-ID: NDRG2_MOUSE
UniprotKB: Q9QYG0
UniParc: UPI000000192A, UPI00001E8DF5
EMBL: BC012963, AK173136, AK154597, AK168011, AB033921, AK158900, AK076514
Ensembl: ENSMUSG00000004558
KO: mmu:29811
Nucleutide sequences
EMBL-CDS: AAH12963.1, BAC36373.1, BAE39998.1, BAE34721.1, BAA85882.1, BAE32700.1, BAD32414.1
Ensembl_TRS: ENSMUST00000004673, ENSMUST00000111632
Protein sequencees
Ensembl_PRO: ENSMUSP00000107259, ENSMUSP00000004673
RefSeq: XP_036014553.1, NP_001347202.1, NP_001347200.1, NP_001347194.1, XP_036014554.1, NP_001347196.1, NP_001347205.1, NP_001347203.1, NP_001347201.1, XP_036014556.1, NP_038892.1, NP_001347195.1, NP_001347198.1, NP_001347193.1, XP_036014555.1, NP_001347197.1, NP_001139431.1, NP_001347199.1
Others
UniRef100: UniRef100_Q9QYG0
UniRef90: UniRef90_Q9QYG0
UniRef50: UniRef50_Q9UN36
UniGene: Mm.26722
CCDS: CCDS49486.1, CCDS27047.1

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