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29781 NCAPH2

29781

NCAPH2

non-SMC condensin II complex subunit H2

protein-coding

Homo sapiens

基因描述

Type Description
Definition non-SMC condensin II complex subunit H2

研究结论

Date Results Publications
2020-06-06 10:30:00 NCAPH2 promotes telomere stability, possibly through a direct interaction with the TRF1 shelterin component 31026066
2019-02-23 12:57:00 Data found that the abundance of CAP-H2 is increased in mitosis by a Plk1 kinase activity-dependent manner and that inhibition of Plk1 induces a degradation of CAP-H2 through Cdc20-mediated ubiquitin-proteasome machinery. These results suggest that the expression levels of CAP-H2 are regulated by Plk1 and Cdc20 for proper chromosomal organization during mitosis. 28717250
2017-11-11 10:07:00 Condensin II(CAP-D3 and CAP-H2) and GAIT subunits associate with L1 RNA in a co-dependent manner, independent of IFN-gamma. These findings suggest that cooperation between the Condensin II and GAIT complexes may facilitate a novel mechanism of L1 repression, thus contributing to the maintenance of genome stability in somatic cells 29028794
2017-07-01 13:01:00 Results suggest that DNA methylation in the NCAPH2/LMF2 promoter region is associated with hippocampal atrophy through apoptosis 27356276
2016-07-16 11:35:00 DNA methylation in the NCAPH2/LMF2 promoter region is significantly decreased in Alzheimer disease. 26742120

名称对应

Type IDs
Synonymous CAPH2
Gene
UniProtKB-ID: CNDH2_HUMAN
UniprotKB: Q6IBW4
UniParc: UPI0001662FE0, UPI0000207A5C, UPI0000207A64, UPI0000207A65
EMBL: BC001833, BC009441, BC001509, BC000473, BC014939, CR456604, CH471138, AL021682, U62317, BC001937
Ensembl: ENSG00000025770
KO: hsa:29781
Nucleutide sequences
EMBL-CDS: EAW73556.1, AAB03345.1, AAH01833.1, EAW73552.1, AAH14939.2, EAW73554.1, CAA16670.1, AAH01937.1, CAG30490.1, AAH09441.1, AAH01509.1, AAH00473.1
Ensembl_TRS: ENST00000420993, ENST00000395698, ENST00000299821
Protein sequencees
Ensembl_PRO: ENSP00000410088, ENSP00000299821, ENSP00000379050
RefSeq: XP_016884282.1, NP_689512.2, NP_055366.3, XP_005261969.1, NP_001171940.1, XP_011528987.1
Others
UniRef100: UniRef100_Q6IBW4
UniRef90: UniRef90_Q6IBW4
UniRef50: UniRef50_Q6IBW4
UniGene: Hs.730607
CCDS: CCDS43038.1, CCDS54546.1, CCDS14094.2

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